Results 11 to 20 of about 116,690 (300)

miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7. [PDF]

EBioMedicine, 2019
Pleural fibrosis is defined as excessive depositions of matrix components that result in pleural tissue architecture destruction and dysfunction. In severe cases, the progression of pleural fibrosis leads to lung entrapment, resulting in dyspnea and respiratory failure.
Wang M, Xiong L, Jiang LJ, Lu YZ, Liu F, Song LJ, Xiang F, He XL, Yu F, Shuai SY, Ma WL, Ye H.   +11 more
europepmc   +4 more sources

Cellular Response to Bone Morphogenetic Proteins-2 and -7 Covalently Bound to Photocrosslinked Heparin–Diazoresin Multilayer

Biomolecules, 2023
Despite the plethora of research that exists on recombinant human bone morphogenetic protein-2 and -7 (rhBMP-2 and rhBMP-7) and has been clinically approved, there is still a need to gain information that would allow for their more rational use in bone ...
Magdalena Wytrwal, Małgorzata Sekuła-Stryjewska, Agata Pomorska, Ewa Oclon, Ewa Zuba-Surma, Szczepan Zapotoczny, Krzysztof Szczubiałka   +6 more
doaj   +1 more source

Heterodimeric BMP-2/7 antagonizes the inhibition of all-trans retinoic acid and promotes the osteoblastogenesis. [PDF]

PLoS ONE, 2013
OBJECTIVES: Hypervitaminosis A and alcoholism can result in a low mineral density and compromised regenerative capacity of bone, thus delaying implant osteointegration.
Wenjuan Bi, Zhiyuan Gu, Yuanna Zheng, Xiao Zhang, Jing Guo, Gang Wu   +5 more
doaj   +1 more source

Sulforaphane Ameliorates Diabetes-Induced Renal Fibrosis through Epigenetic Up-Regulation of BMP-7 [PDF]

Diabetes & Metabolism Journal, 2021
Background The dietary agent sulforaphane (SFN) has been reported to reduce diabetes-induced renal fibrosis, as well as inhibit histone deacetylase (HDAC) activity.
Lili Kong, Hongyue Wang, Chenhao Li, Huiyan Cheng, Yan Cui, Li Liu, Ying Zhao   +6 more
doaj   +1 more source

Role of BMP-7 on biological parameters osseointegration of dental implants: Preliminary results of a preclinical study

Frontiers in Bioengineering and Biotechnology, 2023
The aim of this work was to analyze and compare the effect of bone morphogenetic protein-7 on biological parameters related to implant osseointegration in an experimental animal model.
Nansi López-Valverde, Javier Aragoneses, Antonio López-Valverde, Cinthia Rodríguez, Juan Manuel Aragoneses   +4 more
doaj   +1 more source

Guiding synovial inflammation by macrophage phenotype modulation: An in vitro study towards a therapy for osteoarthritis [PDF]

, 2016
Objective: The aims of this study were to modulate inflammation in synovial explants with the compounds: dexamethasone, rapamycin, bone morphogenetic protein 7 (BMP-7) and pravastatin, and to investigate the ...
Bastiaansen-Jenniskens, Y.M. (Yvonne), Bayon, Y. (Yves), Osch, G.J.V.M. (Gerjo) van, Utomo, L. (Lizette), Verhaar, J.A.N. (Jan)   +4 more
core   +4 more sources

Effects of ergosteroside combined risedronate on fracture healing and BMP-2, BMP-7 and VEGF expression in rats

Acta Cirúrgica Brasileira, 2021
Purpose To evaluate the effect of ergosterol combined with risedronate on fracture healing. Methods Sixty male Sprague Dawley fracture model rats were assigned into group A (n=20), group B (n=20), and group C (n=20) at random.
Xiaofeng Xu, Wenyu Hui, Nian Liu, Yong Zhang   +3 more
doaj   +1 more source

Renal Bone Morphogenetic Protein-7 Protects against Diabetic Nephropathy [PDF]

Journal of the American Society of Nephrology, 2006
Longstanding diabetes causes renal injury with early dropout of podocytes, albuminuria, glomerular and tubulointerstitial fibrosis, and progressive renal failure. The renal pathology seems to be driven, in part, by TGF-beta and is associated with a loss of renal bone morphogenic protein-7 (BMP-7) expression.
Shinong, Wang, Mark, de Caestecker, Jeffrey, Kopp, Grace, Mitu, Janine, Lapage, Raimund, Hirschberg   +5 more
openaire   +2 more sources

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole, Differ, Christopher, Klatte-Schulz, Franka, Knaus, Petra, Minkwitz, Susann, Wildemann, Britt   +5 more
core   +1 more source