The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells ...
Martin Waselau +11 more
doaj +1 more source
The aim of the study is to evaluate the parameter of fusion success of Bone Morphogenetic Protein-7 (BMP-7 or osteogenic pro- tein-1) versus autograft (autogenous iliac crest bone graft (ICBG) or cancellous bone) in posterolateral fusion (PLF) of the ...
Eko Agus Subagio +7 more
doaj +1 more source
Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]
The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas +5 more
core +1 more source
Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling [PDF]
Bone morphogenetic proteins (BMPs) control multiple cellular processes in embryos and adult tissues. BMPs signal through the activation of type I BMP receptor kinases, which then phosphorylate SMADs 1/5/8.
Campbell, David +7 more
core +3 more sources
Therapy of delayed consolidation of mandible fractures
The aim of the study is to improve the effectiveness of treatment for delayed consolidation of mandibular fractures by developing and clinical testing of integrated therapy using growth factors and bone morphogenetic protein-2.
N.Н. Idashkina +3 more
doaj +1 more source
Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/b-tricalcium phosphate porous ceramics [PDF]
The association of bone morphogenetic proteins (BMPs) with calcium phosphate bioceramics is known to confer them osteoinductive properties. The aim of this study was to evaluate the surface properties, especially regarding recombinant human BMP-2 (rhBMP-
Alam +38 more
core +3 more sources
Bone Morphogenetic Protein-7 Inhibits EMT-Associated Genes in Breast Cancer
Background/Aims: Bone morphogenetic protein-7 (BMP7) has been shown to reduce the severity of injury-induced fibrosis through counteracting the fibrotic effects of transforming growth factor β 1 (TGFβ1).
Xuexiang Ying, Yunpo Sun, Pingqing He
doaj +1 more source
The posterior use of BMP-2 in cervical deformity surgery does not result in increased early complications: A prospective multicenter study [PDF]
Study designProspective cohort study.ObjectivesTo describe the rate of short-term complications following the posterior use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in cervical deformity (CD) surgery.MethodsCD patients from 2013 to ...
Albert, Todd J +13 more
core +2 more sources
Deletion of the sequence encoding the tail domain of the bone morphogenetic protein type 2 receptor reveals a bone morphogenetic protein 7-specific gain of function. [PDF]
The bone morphogenetic protein (BMP) type II receptor (BMPR2) has a long cytoplasmic tail domain whose function is incompletely elucidated. Mutations in the tail domain of BMPR2 are found in familial cases of pulmonary arterial hypertension.
Patricio A Leyton +8 more
doaj +1 more source
Bone Morphogenetic Protein‐7 Enhances Cementoblast Function In Vitro
Background: Bone morphogenetic protein (BMP)‐7 is a potent bone‐inducing factor and was shown to promote periodontal regeneration in vivo and in vitro; however, to our knowledge, the specific effect of BMP‐7 on cementoblasts has not been defined. We aimed to investigate the effects of BMP‐7 on cementoblasts, which are cells responsible for tooth root ...
Hakkı, Sema S. +6 more
openaire +2 more sources

