Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou +3 more
wiley +1 more source
Bone morphogenetic proteins (BMPs) at the forefront of ocular diseases and therapeutics. [PDF]
Shi Y, Zhang J, Duan W, Gao L, Liu Y.
europepmc +1 more source
The role of bone morphogenetic proteins in myeloma cell survival
Multiple myeloma is characterized by slowly growing clones of malignant plasma cells in the bone marrow. The malignant state is frequently accompanied by osteolytic bone disease due to a disturbed balance between osteoblasts and osteoclasts.
Holien, Toril, Sundan, Anders
core
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
Predictive potential of hepatocyte growth factor and bone morphogenetic proteins in lymphatic metastasis of breast cancer. [PDF]
Cong BB +4 more
europepmc +1 more source
A new MMP-mediated prodomain cleavage mechanism to activate bone morphogenetic proteins from the extracellular matrix. [PDF]
Furlan AG +8 more
europepmc +1 more source
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley +1 more source
Interaction Between Thyroid Hormones and Bone Morphogenetic Proteins in the Regulation of Steroidogenesis by Granulosa Cells. [PDF]
Motohashi K +6 more
europepmc +1 more source
Applications of Bone Morphogenetic Proteins in Dentistry: A Bibliometric Analysis. [PDF]
Ahmad P, Della Bella E, Stoddart MJ.
europepmc +1 more source
Genetic variants in bone morphogenetic proteins signaling pathway might be involved in palatal rugae phenotype in humans. [PDF]
Silva-Sousa AC +9 more
europepmc +1 more source

