Results 1 to 10 of about 237,429 (280)
miRNA-128 modulates bone neoplasms cells proliferation and migration through the WNT/β-catenin and EMT signal pathways [PDF]
Journal of Orthopaedic Surgery and Research, 2021 Background Bone neoplasms present poor prognosis due to recurrence and metastasis. Although the role microRNAs (miRNAs) in inhibiting growth and metastasis of bone neoplasms has been investigated, the underlying potential molecular mechanisms mediated by
Yang Li +4 more
doaj +2 more sources
Bone marrow niches in myeloid neoplasms [PDF]
Pathology International, 2019 Pathological phenotypes of myeloid neoplasms are closely related to genetic/chromosomal abnormalities of neoplastic cells whereas the bone marrow microenvironment, including stromal elements and hematopoietic stem cell niche cells, have a great influence on the differentiation/proliferation of both hematopoietic and neoplastic cells.
Masanobu Kitagawa +3 more
openaire +4 more sources
Prognostic value of C-reactive protein levels in patients with bone neoplasms: A meta-analysis. [PDF]
PLoS ONE, 2018 The aim of this study was to conduct a meta-analysis of retrospective studies that investigated the association of preoperative C-reactive protein (CRP) levels with the overall survival (OS) of patients with bone neoplasms.A detailed literature search ...
Wenyi Li +4 more
doaj +2 more sources
Primary bone neoplasms in dogs: 90 cases [PDF]
Pesquisa Veterinária Brasileira, 2012 A retrospective study of necropsy and biopsy cases of 90 primary bone tumors (89 malignant and one benign) in dogs received over a period of 22 years at the Laboratório de Patologia Veterinária, Universidade Federal de Santa Maria, was performed ...
Maria E. Trost +7 more
doaj +2 more sources
Bone marrow niche dysregulation in myeloproliferative neoplasms
Haematologica, 2020 The bone marrow niche is a complex and dynamic structure composed of a multitude of cell types which functionally create an interactive network facilitating hematopoietic stem cell development and maintenance. Its specific role in the pathogenesis, response to therapy, and transformation of myeloproliferative neoplasms has only recently been explored ...
Donal P. McLornan +2 more
openaire +6 more sources
β-elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells. [PDF]
Oncol Lett, 2018 The purpose of the present study was to investigate the anticancer effects of β-elemene and paclitaxel for bone neoplasms. MTT assay, reverse transcription-quantitative polymerase chain reaction, western blotting, flow cytometry and immunostaining were used to analyze the combined effects of β-elemene and paclitaxel both in vitro and in vivo.
Wang Z, Li Y, Zhou F, Piao Z, Hao J.
europepmc +5 more sources
Immunosuppression as a Hallmark of Critical COVID-19: Prospective Study
Cells, 2021 The dysregulation of both the innate and adaptive responses to SARS-CoV-2 have an impact on the course of COVID-19, and play a role in the clinical outcome of the disease.
Elżbieta Kalicińska +13 more
doaj +1 more source
A case report of pediatric acute lymphoblastic leukemia with e8a2 BCR/ABL1 fusion transcript
BMC Medical Genomics, 2022 Background Acute lymphoblastic leukemia is the most common type of cancer in children. Most often it affects the age group between 2 and 5 years of age. Studies have shown an improvement in general survivability, more than 90% 5-year overall survival (OS)
Aleksandra Mroczkowska +8 more
doaj +1 more source
Cardiology Research and Practice, 2021 Background. Platelet reactivity and response to antiplatelet drugs, acetylsalicylic acid (ASA) and clopidogrel, in patients with thrombocytopenia and thrombocythemia can have a potentially important effect on the outcome.
Wiktor Kuliczkowski +11 more
doaj +1 more source
Viruses, 2021 The use of convalescent plasma in the treatment of COVID-19 may lead to a milder course of infection and has been associated with improved outcomes.
Monika Maria Biernat +11 more
doaj +1 more source