miRNA-128 modulates bone neoplasms cells proliferation and migration through the WNT/β-catenin and EMT signal pathways [PDF]
Background Bone neoplasms present poor prognosis due to recurrence and metastasis. Although the role microRNAs (miRNAs) in inhibiting growth and metastasis of bone neoplasms has been investigated, the underlying potential molecular mechanisms mediated by
Yang Li +4 more
doaj +3 more sources
Prognostic value of C-reactive protein levels in patients with bone neoplasms: A meta-analysis. [PDF]
The aim of this study was to conduct a meta-analysis of retrospective studies that investigated the association of preoperative C-reactive protein (CRP) levels with the overall survival (OS) of patients with bone neoplasms.A detailed literature search ...
Wenyi Li +4 more
doaj +3 more sources
β-elemene enhances anticancer bone neoplasms efficacy of paclitaxel through regulation of GPR124 in bone neoplasms cells. [PDF]
The purpose of the present study was to investigate the anticancer effects of β-elemene and paclitaxel for bone neoplasms. MTT assay, reverse transcription-quantitative polymerase chain reaction, western blotting, flow cytometry and immunostaining were ...
Wang Z, Li Y, Zhou F, Piao Z, Hao J.
europepmc +2 more sources
Long Non-Coding RNA HULC Promotes Progression of Bone Neoplasms. [PDF]
Background Bone neoplasms are common in humans and have high lethality. Recently, great progress has been made in understanding the pathophysiological mechanisms, but little is known about the molecular and genetic networks involved. Material/Methods qRT-
Zhang T, Wan CY, Mei XL, Jia P, Wang MJ.
europepmc +2 more sources
The Geometric Osteotomy: Joint Preservation in Juxta‐Articular Surface Bone Neoplasms [PDF]
Purpose. To present the oncologic and functional results of a consecutive series of patients treated by geometric osteotomy and allograft reconstruction for juxta-articular surface bone neoplasms. Patients. Twelve consecutive patients (mean age 28 years)
Eric Masterson +4 more
openalex +2 more sources
A hostel for the hostile: the bone marrow niche in hematologic neoplasms [PDF]
Our understanding of the biology of the normal hematopoietic stem cell niche has increased steadily due to improved murine models and sophisticated imaging tools. Less well understood, but of growing interest, is the interaction between cells in the bone
Daniela S. Krause, David T. Scadden
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Genetic effect of basal metabolic rate on the benign neoplasm of bone and articular cartilage: a Mendelian randomization study [PDF]
BackgroundPrevious studies have found an association between basal metabolic rate (BMR) and various malignant neoplasms, including bone tumors. BMR is also associated with bone mineral density, but the causality between BMR and benign neoplasms of bone ...
Guijin Huang +11 more
doaj +2 more sources
Lymphocyte subsets in haematological patients with COVID-19: Multicentre prospective study
The role of immune dysregulation in the course and prognosis of COVID-19 is not clearly established. In particular, immune status in specific populations such as haematological patients, who have an impaired immunological system, has not been described ...
Elżbieta Kalicińska +12 more
doaj +1 more source
Immunosuppression as a Hallmark of Critical COVID-19: Prospective Study
The dysregulation of both the innate and adaptive responses to SARS-CoV-2 have an impact on the course of COVID-19, and play a role in the clinical outcome of the disease.
Elżbieta Kalicińska +13 more
doaj +1 more source
A case report of pediatric acute lymphoblastic leukemia with e8a2 BCR/ABL1 fusion transcript
Background Acute lymphoblastic leukemia is the most common type of cancer in children. Most often it affects the age group between 2 and 5 years of age. Studies have shown an improvement in general survivability, more than 90% 5-year overall survival (OS)
Aleksandra Mroczkowska +8 more
doaj +1 more source

