Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis +19 more
wiley +1 more source
Changes in epiphyseal bone, subchondral bone plate and epiphyseal trabecular bone in surgically and chemically induced rat models of osteoarthritis [PDF]
Jukka Morko +6 more
openalex +1 more source
Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee +7 more
wiley +1 more source
Optimization of Metal Injection Molding Processing Conditions for Reducing Black Lines and Meld Lines in Bone Plates. [PDF]
Lin CM, Yen PY, Tan CM.
europepmc +1 more source
Optimisation of composite bone plates for ulnar transverse fractures
N.D. Chakladar +2 more
openalex +1 more source
Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli +14 more
wiley +1 more source
Distribution of bone fragments in angled shots: an experimental study conducted on composite models containing artificial bone plates. [PDF]
Geisenberger D +5 more
europepmc +1 more source
Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi +7 more
wiley +1 more source
Bone Plates Runout Prediction Through Tensile Strength and Geometric Properties for Regulatory Mechanical Testing. [PDF]
Bologna FA, Audenino AL, Terzini M.
europepmc +1 more source

