Orthopaedic trauma is a predominant cause of patient mortality and prompt surgical interventions. The locking compression plate (LCP) is widely regarded as a gold standard in treating bone fractures.
Abdulsalam A. Al-Tamimi +5 more
doaj +1 more source
BIOMINERALOGICAL INVESTIGATION OF APATITE PIEZOELECTRICITY
Investigation of apatite piezoelectricity was conducted in order to assess piezoelectric properties of bone. In the first stage, mineralogical analysis of different apatite crystals, regarding their purity and fitness for the experiments was performed ...
M. Pawlikowski
doaj +1 more source
This study was designed to investigate the effects of hydroxyapatite (HA) ceramic implants (HA cylinders, perforated HA plates, and nonperforated HA plates) on the healing of bone defects, addressing biocompatibility, biodegradability, osteoconductivity,
Lenka Kresakova +11 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Re-Fracture as Impact of Rigid Implant and Bone Osteoporosis: A Case Report
Background: The increasing life expectancy of the world population associated with osteopenia and osteoporosis leads to low-energy fractures, especially in the lower limb.
Huda Fajar Arianto, Yunus Basrewan
doaj +1 more source
Controlled rotation of long bones by guided growth: A proof of concept study of a novel plate in cadavers [PDF]
Ahmed Abdul‐Hussein Abood +7 more
openalex +1 more source
An Elastic Analysis of a Plated Bone to Determine Fracture Gap Motion [PDF]
An elastic analysis to determine fracture gap motions occurring in the osteotomized and plated canine femur was performed using the finite element program NASTRAN.
Cooke, F. W., Vannah, W. M.
core +1 more source
An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS +8 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Age-related changes in trabecular bone microstructures: global and local morphometry [PDF]
Introduction: A recently developed method allows investigating trabecular bone on an elemental (rod/plate) level. With this method, it is possible to measure local morphometric parameters such as thickness or orientation directly on the extracted rods ...
Müller, R., Stauber, M.
core

