Results 351 to 360 of about 2,650,892 (412)

Polyhedron‐Like Biomaterials for Innervated and Vascularized Bone Regeneration

Advances in Materials, 2023
Neural‐vascular networks are densely distributed through periosteum, cortical bone, and cancellous bone, which is of great significance for bone regeneration and remodeling.
Hongjian Zhang, Meng Zhang, Dong Zhai, Chen Qin, Yufeng Wang, Jingge Ma, Zhuang Hui, Zhe Shi, Liang Wang, Chengtie Wu   +9 more
semanticscholar   +1 more source

Photosensitive and Conductive Hydrogel Induced Innerved Bone Regeneration for Infected Bone Defect Repair

Advanced Healthcare Materials, 2022
Repairing infected bone defects is a challenge in the field of orthopedics because of the limited self‐healing capacity of bone tissue and the susceptibility of refractory materials to bacterial activity.
Xirui Jing, Chao Xu, Weijie Su, Qiuyue Ding, Bing Ye, Yanlin Su, Keda Yu, Lian Zeng, Xu Yang, Yanzhen Qu, Kaifang Chen, Tingfang Sun, Zhiqiang Luo, Xiaodong Guo   +13 more
semanticscholar   +1 more source

Regulating Macrophage Polarization in High Glucose Microenvironment Using Lithium‐Modified Bioglass‐Hydrogel for Diabetic Bone Regeneration

Advanced Healthcare Materials, 2022
Diabetes mellitus is a chronic metabolic disease with a proinflammatory microenvironment, causing poor vascularization and bone regeneration. Due to the lack of effective therapy and one‐sided focus on the direct angiogenic properties of biomaterials and
Zerui Wu, Jiaxiang Bai, Gaoran Ge, Tao Wang, Shuo Feng, Qiaoqiao Ma, Xiaolong Liang, Wenming Li, Wei Zhang, Yaozeng Xu, K. Guo, W. Cui, Guo‐chun Zha, D. Geng   +13 more
semanticscholar   +1 more source

A Logic‐Based Diagnostic and Therapeutic Hydrogel with Multistimuli Responsiveness to Orchestrate Diabetic Bone Regeneration

Advances in Materials, 2021
The regeneration of diabetic bone defects remains challenging as the innate healing process is impaired by glucose fluctuation, reactive oxygen species (ROS), and overexpression of proteinases (such as matrix metalloproteinases, MMPs). A “diagnostic” and
Dize Li, Kaiwen Chen, Han Tang, Shanshan Hu, Liangjing Xin, Xuan Jing, Qingqing He, Si Wang, Jinlin Song, Li Mei, R. Cannon, P. Ji, Huanan Wang, Tao Chen   +13 more
semanticscholar   +1 more source

Coaxially Fabricated Dual‐Drug Loading Electrospinning Fibrous Mat with Programmed Releasing Behavior to Boost Vascularized Bone Regeneration

Advanced Healthcare Materials, 2022
In clinical treatment, the bone regeneration of critical‐size defects is desiderated to be solved, and the regeneration of large bone segment defects depends on early vascularization.
Jinjie Cui, Xingge Yu, Bin Yu, X. Yang, Zeyu Fu, Jianyu Wan, Min-Ying Zhu, Xudong Wang, Kaili Lin   +8 more
semanticscholar   +1 more source

Bone Microenvironment‐Mimetic Scaffolds with Hierarchical Microstructure for Enhanced Vascularization and Bone Regeneration

Advanced Functional Materials, 2022
Microchannel networks within engineered 3D scaffold can allow nutrient exchange and rapid blood vessels formation. However, fabrication of a bone microenvironment‐mimicking scaffold with hierarchical micro/nanofibrous and microchannel structures is still
Yujie Ha, Xiaojun Ma, Shikai Li, Tao Li, Zhihui Li, Yuhan Qian, Muhammad Shafiq, Jinwu Wang, Xiaojun Zhou, Chuanglong He   +9 more
semanticscholar   +1 more source

Recent Advances in 3D Printing of Smart Scaffolds for Bone Tissue Engineering and Regeneration

Advances in Materials
The repair and functional reconstruction of bone defects resulting from severe trauma, surgical resection, degenerative disease, and congenital malformation pose significant clinical challenges.
Xun Yuan, Wei Zhu, Zhongyuan Yang, Ning He, Feng Chen, Xiaoxiao Han, Kun Zhou   +6 more
semanticscholar   +1 more source

Advanced Strategies of Biomimetic Tissue‐Engineered Grafts for Bone Regeneration

Advanced Healthcare Materials, 2021
The failure to repair critical‐sized bone defects often leads to incomplete regeneration or fracture non‐union. Tissue‐engineered grafts have been recognized as an alternative strategy for bone regeneration due to their potential to repair defects.
Chang Xie, Jinchun Ye, Renjie Liang, Xudong Yao, Xinyu Wu, Yiwen Koh, Wei Wei, Xianzhu Zhang, H. Ouyang   +8 more
semanticscholar   +1 more source

Bone Regeneration and Repair

Current Stem Cell Research & Therapy, 2010
In the face of mounting clinical demand, and armed with reconstructive techniques that are technically challenging and frequently result in suboptimal patient outcomes, increasing focus is being placed on tissue engineering and regenerative medicine as a potential source of novel skeletal reconstructive approaches.
Nicholas J, Panetta, Deepak M, Gupta, Michael T, Longaker   +2 more
openaire   +2 more sources

Capturing Magnesium Ions via Microfluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration.

ACS Nano, 2021
Metal ions are important trace elements in the human body, which directly affect the human metabolism and the regeneration of damaged tissues. For instance, the advanced combination of magnesium ions (Mg2+) and bone repair materials make the composite ...
Zhenyu Zhao, Gen Li, Huitong Ruan, Keyi Chen, Zhengwei Cai, Guanghua Lu, Runmin Li, L. Deng, Ming Cai, W. Cui   +9 more
semanticscholar   +1 more source