Results 221 to 230 of about 2,011,561 (382)

Immune and Angiogenic Profiling of Mesenchymal Stem Cell Functions in a Subcutaneous Microenvironment for Allogeneic Islet Transplantation

Advanced Science, EarlyView.
With emphasis on a diabetic state, this study highlights the role of mesenchymal stem cells (MSCs) in enhancing vascularization and modulating immune responses within a subcutaneous platform for cell transplantation for type 1 diabetes (T1D). Comprehensive profiling of MSC‐induced angiogenic and immune responses, provides insight into the role of MSCs ...
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Ashley L. Joubert, Nathanael Hernandez, Tommaso Bo, Octavio I. Sauceda‐Villanueva, Marzia Conte, Letizia Franco, Marco Farina, Gabrielle E. Rome, Yitian Xu, Junjun Zheng, Lissenya B. Argueta, Jean A. Niles, Fotis Nikolos, Corrine Ying Xuan Chua, Shu‐Hsia Chen, Joan E. Nichols, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Tripartite motif-containing 27 negatively regulates NF-κB activation in bone remodeling. [PDF]

Mol Med
Kim K, Kim JH, Kim I, Seong S, Kook H, Koh JT, Kim N.   +6 more
europepmc   +1 more source

1124 Remodeling Simulation of Cancellous Bone at Bone-Screw Interface in Vertebral Body

, 2000
Motoi SHIBUTANI, Ken-ichi TSUBOTA, Taiji ADACHI, Yoshihiro TOMITA   +3 more
openalex   +2 more sources

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

Cryogels with controllable physico-chemical properties as advanced delivery systems for biomedical applications

Materials Today Bio
Enhancing the spatiotemporal control of drug delivery holds significant potential for improving drug bioavailability, minimizing adverse reactions and toxicity, and advancing precision medicine. Traditional hydrogels have been widely recognized for their
Mucong Li, Xuyan Wei, Jiaqian You, Jian Feng, Xiuyu Liu, Jing Zhou, Qianju Wu, Yidi Zhang, Yanmin Zhou   +8 more
doaj  

Immunohistochemical Evaluation of Bone Remodeling Following Compressive Force on Mandibular Condyle. [PDF]

Biology (Basel)
Lyros I, Tsolakis IA, Kotantoula G, Tosios K, George V, Nikitakis N, Ferdianakis E, Lykogeorgos T, Fora E, Tsolakis AI.   +9 more
europepmc   +1 more source

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai   +12 more
wiley   +1 more source

Citrate: a key signalling molecule and therapeutic target for bone remodeling disorder. [PDF]

Front Endocrinol (Lausanne)
Liu Q, Xue Y, Guo J, Tao L, Zhu Y.
europepmc   +1 more source

Bone Marrow Is a Reservoir of Repopulating Mesangial Cells during Glomerular Remodeling

, 2001
Takahito Ito, Akira Suzuki, Enyu Imai, Masaru Okabe, Masatsugu Hori   +4 more
openalex   +1 more source

Targeting Splenic Myeloid Cells with Nanobiologics to Prevent Postablative Pancreatic Cancer Recurrence via Inducing Antitumor Peripheral Trained Immunity

Advanced Science, EarlyView.
Using a preclinical pancreatic cancer model, we identified that tumor progression restructures splenic immunity via myeloid cell expansion. MDCa@RBC‐Alipo nanobiologics were engineered to epigenetically and metabolically reprogram splenic myeloid cells, alleviating post‐ablation immunosuppression.
Shengbo Wu, Weichen Xu, Xuexia Shan, Liping Sun, Shuo Liu, Xixi Sun, Shaoyue Li, Xiaodong Hou, Xiaowan Bo, Chengzhong Peng, Bin Huang, Huixiong Xu, Wenwen Yue   +12 more
wiley   +1 more source