Results 321 to 330 of about 2,011,561 (382)

Unraveling devitalization: its impact on immune response and ectopic bone remodeling from autologous and allogeneic callus mimics. [PDF]

Stem Cells Transl Med
de Silva L, van den Beucken JJJP, Rosenberg AJWP, Longoni A, Gawlitta D.   +4 more
europepmc   +1 more source

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

Advanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao, Siwen Chen, Hua Chao, Zihao Li, Hao Yang, Dongying Chen, Sifang Li, Shuai Zhang, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Tangming Guan, Yiwen Zhang, Wende Li, Hui Liu   +16 more
wiley   +1 more source

Role of Pulsed Electromagnetic Field on Alveolar Bone Remodeling during Orthodontic Retention Phase in Rat Models. [PDF]

Dent J (Basel)
Maulana H, Yueniwati Y, Permatasari N, Suyono H.   +3 more
europepmc   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Europium-Containing Nanospheres for Treating Ovariectomy-Induced Osteoporosis: Targeted Bone Remodeling and Macrophage Polarization Modulation. [PDF]

Int J Nanomedicine
Wang YC, Cai MT, Chen MH, Tung FI, Chen MH, Liu TY.   +5 more
europepmc   +1 more source

Exceptional bone remodeling over composite restoration in the management of external root resorption: A case report. [PDF]

SAGE Open Med Case Rep
Zaccheo F, Petroni G, Fiorillo L, Heboyan A, Carnevale G, Calapaj M, Cervino G, Tallarico M.   +7 more
europepmc   +1 more source

Vitronectin regulates osteoclastogenesis and bone remodeling in a mouse model of osteoporosis. [PDF]

Anat Cell Biol
Nakashima M, Suzuki A, Hashimoto K, Yamashita M, Fujiwara Y, Miyamoto Y.   +5 more
europepmc   +1 more source

Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion. [PDF]

Prog Orthod
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F.   +7 more
europepmc   +1 more source

Pip5k1c expression in osteocytes regulates bone remodeling in mice. [PDF]

J Orthop Translat
Lin S, Tao C, Yan Q, Gao H, Qin L, Zhong Y, Yao Q, Zhang P, Yang J, Zou X, Xiao G.   +10 more
europepmc   +1 more source

A review of mathematical modeling of bone remodeling from a systems biology perspective. [PDF]

Front Syst Biol
Cook CV, Lighty AM, Smith BJ, Ford Versypt AN.   +3 more
europepmc   +1 more source