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Annals of the New York Academy of Sciences, 2006
Abstract: The skeleton is a metabolically active organ that undergoes continuous remodeling throughout life. Bone remodeling involves the removal of mineralized bone by osteoclasts followed by the formation of bone matrix through the osteoblasts that subsequently become mineralized.
Dimitrios J, Hadjidakis +1 more
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Abstract: The skeleton is a metabolically active organ that undergoes continuous remodeling throughout life. Bone remodeling involves the removal of mineralized bone by osteoclasts followed by the formation of bone matrix through the osteoblasts that subsequently become mineralized.
Dimitrios J, Hadjidakis +1 more
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Hematopoiesis and bone remodeling [PDF]
Blood, 2011 Erythropoietin (Epo) is a polypeptide hormone produced in kidney. It stimulates the proliferation of erythroid progenitor cells in response to hypoxia. In this issue of Blood , the report of Singbrant et al clearly shows the indirect effect of Epo on bone remodeling and its importance for the Epo-
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British Dental Journal, 1992
Bone is a specialised connective tissue that, together with cartilage, makes up the skeleton. These tissues serve three functions: (a) mechanical support and site of muscle attachment for locomotion; (b) protection for vital organs and bone marrow and (c) a metabolic reserve of ions for the entire organism, especially calcium and phosphate.
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Bone is a specialised connective tissue that, together with cartilage, makes up the skeleton. These tissues serve three functions: (a) mechanical support and site of muscle attachment for locomotion; (b) protection for vital organs and bone marrow and (c) a metabolic reserve of ions for the entire organism, especially calcium and phosphate.
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Bone remodelling in osteoarthritis
Nature Reviews Rheumatology, 2012The classical view of the pathogenesis of osteoarthritis (OA) is that subchondral sclerosis is associated with, and perhaps causes, age-related joint degeneration. Recent observations have demonstrated that OA is associated with early loss of bone owing to increased bone remodelling, followed by slow turnover leading to densification of the subchondral
Maxime A. Gallant, David B. Burr
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Proteases and bone remodelling
Cytokine & Growth Factor Reviews, 2009Bone remodelling is regulated by osteogenic cells which act individually through cellular and molecular interaction. These interactions can be established either through a cell-cell contact, involving molecules of the integrin family, or by the release of many polypeptidic factors and/or their soluble receptor chains.
Valérie Trichet +12 more
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Bone remodelling and orthodontics
The European Journal of Orthodontics, 1985odontics is based on the predictable remodelling of bone surrounding and supporting the teeth in response to stimuli generated or brought about by orthodontic appliances. Progress in orthodontics depends on further insight into bone remodelling which will make prognosis and relapse more predictable as well.
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2014
Skeletal buildup and maintenance is ensured by modeling and remodeling processes. Bone modeling works mainly during organism growth and is characterized by bone formation prevailing on resorption: The two processes are carried out simultaneously but not at the same location.
Brunetti G. +2 more
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Skeletal buildup and maintenance is ensured by modeling and remodeling processes. Bone modeling works mainly during organism growth and is characterized by bone formation prevailing on resorption: The two processes are carried out simultaneously but not at the same location.
Brunetti G. +2 more
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Critical Reviews™ in Eukaryotic Gene Expression, 2009
Bone modeling adapts structure to loading by changing bone size and shape and removes damage and so maintains bone strength. Remodeling is initiated by damage producing osteocyte apoptosis, which signals the location of damage via the osteocyte-canalicular system to endosteal lining cells that form the canopy of a bone remodeling compartment (BRC ...
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Bone modeling adapts structure to loading by changing bone size and shape and removes damage and so maintains bone strength. Remodeling is initiated by damage producing osteocyte apoptosis, which signals the location of damage via the osteocyte-canalicular system to endosteal lining cells that form the canopy of a bone remodeling compartment (BRC ...
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Bone remodelling in osteoporosis
Clinical Rheumatology, 1989Bone remodelling, a highly regulated succession of events, is the temporal sequence of osteoclastic bone resorption and osteoblastic bone formation. Bone loss with age and in osteoporotic patients is due to a disequilibrium between both processus. Bone histomorphometry was the method used to measure these events.
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Central Control of Bone Remodelling
Journal of Neuroendocrinology, 2005The discovery that the brain controls bone remodelling has provided a new paradigm for our understanding of bone biology. This review summarises the genetic, molecular and physiological bases for the central control of bone remodelling and discusses the future directions of this new research field of neuroskeletal biology.
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