Results 111 to 120 of about 641,029 (315)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Development and validation of a nomogram prediction model for perioperative deep vein thrombosis risk in arthroplasty: a retrospective study

Frontiers in Medicine
BackgroundPerioperative monitoring thrombosis has become more crucial due to the rising demand for arthroplasty and shorter hospital stays. We aimed to comprehensively explore immune-inflammatory and hypercoagulable states during perioperative periods ...
Wenming Yang, Wenming Yang, Qitai Lin, Qitai Lin, Zehao Li, Zehao Li, Chuanjie Shan, Chuanjie Shan, Xiaoyu Cheng, Yugang Xing, Yugang Xing, Yongsheng Ma, Yongsheng Ma, Yang Liu, Yang Liu, Meiming Li, Meiming Li, Ruifeng Liang, Wangping Duan, Wangping Duan, Wangping Duan, Pengcui Li, Pengcui Li, Xiaochun Wei, Xiaochun Wei   +24 more
doaj   +1 more source

Low-intensity pulsed ultrasound suppresses synovitis by modulating polarization of synovial macrophages in mice with osteoarthritis

Di-san junyi daxue xuebao, 2019
Objective To investigate the therapeutic effect of low-intensity pulsed ultrasound (LIPUS) on synovitis in a mouse model of osteoarthritis and explore the possible mechanism.
ZHANG Bin, NI Zhenhong, YANG Peng, KUANG Liang, OUYANG Junjie   +4 more
doaj   +1 more source

Return to Sport and Athletic Function in an Active Population After Primary Arthroscopic Labral Reconstruction of the Hip [PDF]

, 2020
Background: Labral reconstruction has been advocated as an alternative to debridement for the treatment of irreparable labral tears, showing favorable short-term results.
Chen, Sarah L., Domb, Benjamin G., Lall, Ajay C., Maldonado, David R., Rosinsky, Philip J., Shapira, Jacob, Walker-Santiago, Rafael, Yelton, Mitchell J.   +7 more
core   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Key roles of the superficial zone in articular cartilage physiology, pathology, and regeneration

Chinese Medical Journal
. The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and mechanical stimuli. The SFZ is not only a crucial
Li Guo, Pengcui Li, Xueqin Rong, Xiaochun Wei, Xiangxiang Pan   +4 more
doaj   +1 more source

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Acute compartment syndrome in tibial fractures: a meta-analysis

BMC Musculoskeletal Disorders
Purpose Acute compartment syndrome (ACS) is a severe complication associated with tibial fractures, which can result in irreversible muscle and nerve damage if not promptly identified and treated. Method This study systematically searched PubMed, EMBASE,
Bo Cong, Haiguang Zhang
doaj   +1 more source

Lived and Care Experiences of Chronic Musculoskeletal Shoulder Pain in Australian Adults: A Qualitative Study

Arthritis Care &Research, EarlyView.
Objective Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centered care and informing local service pathways and care guidelines or standards.
Sonia Ranelli, Joanne E. Jordan, Ilana N. Ackerman, Alison Thorpe, Jennifer G. Persaud, Linda J. Woodhouse, Jason Chua, Ben Horgan, Andrew M. Briggs   +8 more
wiley   +1 more source

The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausal women with osteoporosis: a systematic review and meta-analysis of randomized controlled trials

BMC Musculoskeletal Disorders
Purpose This systematic review and meta-analysis assesses the efficacy of combined calcium and vitamin D supplementation on bone mineral density (BMD) and fracture risk among postmenopausal women with osteoporosis.
Bo Cong, Haiguang Zhang
doaj   +1 more source