Mechanisms responsible for the ability of enoxaparin sodium to inhibit inflammatory responses in the immune microenvironment of bone repair: A transcriptomic sequencing study. [PDF]
Shen X, Yao Q, Ma L.
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Enhancement of in vitro and in vivo bone repair performance of decalcified bone/gelma by desferrioxamine. [PDF]
Wu H +8 more
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Enhancing Bone Repair with β-TCP-Based Composite Scaffolds: A Review of Design Strategies and Biological Mechanisms. [PDF]
Ni X +9 more
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Bioinspired honeycomb-mimetic adaptive hyaluronic acid hydrogel composite scaffold: intelligent prevention and treatment of infection of bone implants and promotion of bone repair. [PDF]
Fu J +13 more
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Vitamin D3-Coated Surfaces and Their Role in Bone Repair and Peri-Implant Biomechanics. [PDF]
Pitol-Palin L +8 more
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Poly(propylene fumarate)/hydroxyapatite nanocomposite/black phosphorus nanosheet phosphate composites for enhanced bone repair. [PDF]
Huang X, Chen J, Ma R, Wang J, Teng Y.
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Mechanically-regulated bone repair
Bone, 2022Fracture healing is a complex, multistep process that is highly sensitive to mechanical signaling. To optimize repair, surgeons prescribe immediate weight-bearing as-tolerated within 24 hours after surgical fixation; however, this recommendation is based on anecdotal evidence and assessment of bulk healing outcomes (e.g., callus size, bone volume, etc.)
Tareq, Anani, Alesha B, Castillo
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The intimate connection, both physical and biochemical, between blood vessels and bone cells has long been recognized. Genetic, biochemical, and pharmacological studies have identified and characterized factors involved in the conversation between endothelial cells (EC) and osteoblasts (OB) during both bone formation and repair.
Richard A D, Carano, Ellen H, Filvaroff
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In the face of mounting clinical demand, and armed with reconstructive techniques that are technically challenging and frequently result in suboptimal patient outcomes, increasing focus is being placed on tissue engineering and regenerative medicine as a potential source of novel skeletal reconstructive approaches.
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