Results 151 to 160 of about 1,831,965 (356)

Quantification of maxillary ontogenetic processes using surface histology and geometric morphometrics [PDF]

, 2021
This thesis investigates the variability of ontogenetic maxillary bone modeling patterns in humans (Homo sapiens) and chimpanzees (Pan troglodytes). Along with sutural growth, bone modeling is the microscopic process by which bones grow in size and model
Schuh, Alexandra
core   +1 more source

A Review of the Clinical Side Effects of Bone Morphogenetic Protein-2.

Tissue engineering. Part B, Reviews, 2016
Bone morphogenetic protein-2 (BMP-2) is currently the only Food and Drug Administration (FDA)-approved osteoinductive growth factor used as a bone graft substitute. However, with increasing clinical use of BMP-2, a growing and well-documented side effect
A. James, Greg LaChaud, Jia Shen, G. Asatrian, Vi Nguyen, Xinli Zhang, K. Ting, C. Soo   +7 more
semanticscholar   +1 more source

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

Advanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong, Jae‐Kook Cha, Wasim Ahmed, Jaewan Kim, Minsup Kim, Kyung Tae Hong, Wonji Choi, Sunjoo Choi, Tae Hyeon Yoo, Hyun‑Ju An, Seung Chan An, Jaemin Lee, Jimin Choi, Sun‐Young Kim, Jun‐Seok Lee, Soonchul Lee, Junwon Choi, Jin Man Kim   +17 more
wiley   +1 more source

An analysis of the role of serum in parathyroid hormone-induced bone resorption in tissue culture [PDF]

, 1967
Paula H. Stern, Lawrence G. Raisz
openalex   +1 more source

Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis

Proceedings of the National Academy of Sciences of the United States of America, 2012
Low estrogen levels undoubtedly underlie menopausal bone thinning. However, rapid and profuse bone loss begins 3 y before the last menstrual period, when serum estrogen is relatively normal.
Ling-Ling Zhu, H. Blair, Jay J Cao, T. Yuen, R. Latif, Lida Guo, I. Tourkova, Jianhua Li, T. Davies, Li Sun, Z. Bian, C. Rosen, A. Zallone, M. New, M. Zaidi   +14 more
semanticscholar   +1 more source

Trifunctional Sialylation‐Based SF‐ZIF@NA Hydrogel for Selective Osteoclast Inhibition and Enhanced Bone‐Vessel Regeneration in Osteoporotic Bone Defects

Advanced Science, EarlyView.
This study introduces the SF‐ZIF@NA hydrogel system for osteoporotic bone defect treatment. The hydrogel inhibits osteoclast fusion by removing sialic acid and preserves the anabolic function of precursor osteoclasts (pOCs). It also releases Zn2⁺ in acidic conditions, promoting osteogenesis and angiogenesis.
Zhengrong Chen, Wenxin Yang, Yong Tang, Qianqian Dong, Kui Huang, Jiulin Tan, Jie Zhang, Juan Cai, Qixiu Yu, Qijie Dai, Jianzhong Xu, Shuquan Guo, Ce Dou, Fei Luo   +13 more
wiley   +1 more source

Assignment of autogenous bone grafts for reconstruction of the alveolar ridge before implant placement

Journal of Oral Medicine and Oral Surgery, 2019
Introduction: Autologous bone is considered to be the “gold standard” for the reconstruction of the reabsorbed alveolar ridges. For small defects, autologous bone samples can be harvested from intraoral donor sites. However, extraoral donor sites are the
Fourcade Claire, Lesclous Philippe, Guiol Julien   +2 more
doaj   +1 more source

CORTISONE-INDUCED BONE RESORPTION IN THE RABBIT [PDF]

, 1961
Elsdon Storey
openalex   +1 more source

Ipriflavone inhibits bone resorption in intact and ovariectomized rats [PDF]

, 2018
The aim of this study was to investigate the possible inhibitory effect of ipriflavone on bone resorption in rats. For this purpose, 10-week-old, intact and ovariectomized (OVX) rats, prelabeled from birth with [3H]tetracycline, were used.
Cecchini, M., Fleisch, H., Mühlbauer, R.   +2 more
core  

Osteoclast-independent bone resorption by fibroblast-like cells [PDF]

, 2003
To date, mesenchymal cells have only been associated with bone resorption indirectly, and it has been hypothesized that the degradation of bone is associated exclusively with specific functions of osteoclasts.
Aicher, Wilhelm K, Claus, Anja, Drynda, Susanne, Gay, Renate E, Gay, Steffen, George, Michael, Hummel, Klaus M, Machner, Andreas, Neumann, Wolfram, Ohtsu, Susumu, Pap, Géza, Pap, Thomas, Schwartz, Peter, Stein, Bernhard   +13 more
core   +3 more sources