Results 241 to 250 of about 258,684 (306)

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Wild bonobos experience unusually low bone resorption during early lactation relative to humans and other mammals. [PDF]

Evol Hum Sci
Behringer V, Sonnweber R, Fruth B, Housman G, Douglas PH, Stevens JMG, Hohmann G, Kivell TL.   +7 more
europepmc   +1 more source

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

FABP4 inhibition suppresses bone resorption and protects against postmenopausal osteoporosis in ovariectomized mice. [PDF]

Nat Commun
Xie Q, Du X, Liang J, Shen Y, Ling Y, Huang Z, Ke Z, Li T, Song B, Wu T, Wang Y, Tao H.   +11 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Impact of elevated sclerostin levels on bone resorption : unravelling structural changes and mineral metabolism disruption. [PDF]

Bone Joint Res
Rodríguez-Ortiz ME, Díaz-Tocados JM, Torralbo AI, Valdés-Díaz K, Rivas-Domínguez A, Guerrero F, Reina-Alfonso I, Naves-Díaz M, Alonso-Montes C, Rodelo-Haad C, Rodríguez M, Muñoz-Castañeda JR, IMIBIC Nephrology Group, López-Baltanas R, Jurado-Montoya D, Barba J, Carmona A, Obrero T, Martínez-Moreno JM, García-Sáez RM, de Mier MVP.   +20 more
europepmc   +1 more source

Biological Control of Bone Resorption in the Middle Ear

, 1991
Richard A. Chole
openalex   +2 more sources

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

An In Vitro Model of Murine Osteoclast-Mediated Bone Resorption. [PDF]

Bio Protoc
Sun X, Wang Z, Tang Y, Weiss SJ, Zhu L.
europepmc   +1 more source

A case of bone resorption in the mentum caused by hyaluronic acid filler in a patient with skeletal Class II jaw deformity [PDF]

Takayuki Nakagawa, Shigehiro Ono, Miyuki Sakuma, Yoko Ishida, Kuniko Mizuta, Ryo Uetsuki, Keijyuro Odan, Yuko Shintaku, Masataka Higuchi, Yutaka Matsushita, Shunichi Kojima, Isao Hirata, Koichi Kato, Tomonao Aikawa   +13 more
openalex   +1 more source