Results 281 to 290 of about 1,847,810 (404)

Differential effects of 1,25-dihydroxyvitamin D3-analogs on osteoblast-like cells and onin vitro bone resorption [PDF]

open access: green, 1995
Gert-Jan C.M. van den Bemd   +4 more
openalex   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek   +9 more
wiley   +1 more source

Interplay between bone marrow adiposity and bone resorption in RANKL-mediated modelled osteoporosis. [PDF]

open access: yesJ Cell Physiol
Rinotas V   +7 more
europepmc   +1 more source

Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy

open access: yesChemPlusChem, EarlyView.
Gold nanoparticles (AuNPs) are widely used in biomedicine, electronics, catalysis, and environmental science. Conventional synthesis relies on harsh chemicals, driving interest in eco‐friendly methods using plants, bacteria, fungi, and algae. Biomolecules like polyphenols, proteins, and fatty acids aid nanoparticle synthesis under mild conditions. This
Youfeng Yue   +3 more
wiley   +1 more source

Gene expression for bone matrix proteins during bone resorption in calcium-deficient rats.

open access: gold, 1994
Keiichi Ohya   +4 more
openalex   +1 more source

Lipid and Corticosteroid Biomarkers Under the Influence of Bisphosphonates

open access: yesDrug Testing and Analysis, EarlyView.
The detection of bisphosphonates is important due to the potential integrity and welfare issues associated with use of these substances. Targeted detection of a nitrogenous and non‐nitrogenous bisphosphonate was detected for 8 h and 28 days post‐administration, respectively.
Kathy Tou   +8 more
wiley   +1 more source

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