Results 111 to 120 of about 97,080 (357)

Biomechanical evaluation of bone screw fixation with a novel bone cement

BioMedical Engineering OnLine, 2015
Bone cement augmentation is commonly used to improve the fixation stability of orthopaedic implants in osteoporotic bone. The aim of this study was to evaluate the effect of novel bone cements on the stability of bone screw fixation by biomechanical testing and to compare them with a conventional Simplex(®)P bone cement and requirements of the ...
Juvonen, Tiina, Nuutinen, Juha-Pekka, Koistinen, Arto P, Kröger, Heikki, Lappalainen, Reijo   +4 more
openaire   +5 more sources

Machine Learning‐Enhanced Optimization for High‐Throughput Precision in Cellular Droplet Bioprinting

Advanced Science, EarlyView.
A high‐throughput droplet‐based cellular bioprinting platform enhanced with machine learning optimizes five key printing parameters—bioink viscosity, nozzle size, printing time, printing pressure, and cell concentration—to enable accurate prediction of droplet size.
Jaemyung Shin, Ryan Kang, Kinam Hyun, Zhangkang Li, Hitendra Kumar, Kangsoo Kim, Simon S. Park, Keekyoung Kim   +7 more
wiley   +1 more source

Systematic review on spheroids from adipose‐derived stem cells: Spontaneous or artefact state?

Journal of Cellular Physiology, Volume 237, Issue 12, Page 4397-4411, December 2022., 2022
Our proposed model of spheroid isolation from liposuction fat. The tissue disintegration releases the pre‐existing spheroids as intact structures. This could be the ideal technique to culture cells in suspension because it avoids a preliminary adhesion isolation step and thus an upstream cell selection.
Anna Barbara Di Stefano, Valentina Urrata, Marco Trapani, Francesco Moschella, Adriana Cordova, Francesca Toia   +5 more
wiley   +1 more source

Cortical bone trajectory fixation cause low compression force in anterior vertebral column

North American Spine Society Journal, 2022
Background: The cortical bone trajectory (CBT) screws follow a caudocephalad and lateral path from the pedicle to the vertebral body. The bone fusion rate of CBT fixation is equal to or lower than conventional pedicle screw fixation.
Sho Fujiwara, Yuichiro Ohnishi, Koichi Iwatsuki, Haruhiko Kishima   +3 more
doaj  

Advancing 6-DoF Instrument Pose Estimation in Variable X-Ray Imaging Geometries [PDF]

IEEE Transactions on Image Processing (2024) (Volume: 33) Page(s): 2462 - 2476
Accurate 6-DoF pose estimation of surgical instruments during minimally invasive surgeries can substantially improve treatment strategies and eventual surgical outcome. Existing deep learning methods have achieved accurate results, but they require custom approaches for each object and laborious setup and training environments often stretching to ...
arxiv   +1 more source

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

Advanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong, Jae‐Kook Cha, Wasim Ahmed, Jaewan Kim, Minsup Kim, Kyung Tae Hong, Wonji Choi, Sunjoo Choi, Tae Hyeon Yoo, Hyun‑Ju An, Seung Chan An, Jaemin Lee, Jimin Choi, Sun‐Young Kim, Jun‐Seok Lee, Soonchul Lee, Junwon Choi, Jin Man Kim   +17 more
wiley   +1 more source

Dynamic Torque Limitation vs Static Torque Limitation for Bone Screws in Pig Bone

Current Directions in Biomedical Engineering
Correctly torquing bone screws is important to achieve good patient outcomes. An automated system has been previously proposed that may allow more objective torquing of bone screws. Here the system is tested vs. a static torque limit in pig bone.
Wilkie Jack, Richard Jordan, Joshi Aditya, McFarlane Zoe, Staiger Mark, Rauter Georg, Möller Knut   +6 more
doaj   +1 more source

Repair of Microdamage in Osteonal Cortical Bone Adjacent to Bone Screw

PLoS ONE, 2014
Up to date, little is known about the repair mode of microdamage in osteonal cortical bone resulting from bone screw implantation. In this study, self-tapping titanium cortical bone screws were inserted into the tibial diaphyses of 24 adult male rabbits.
Qi Zhou, Jin Qi, Jin Shao, Tingjun Ye, Shijing Qiu, Shijing Qiu, Li Wei, Lei Wang, Lianfu Deng   +8 more
openaire   +5 more sources

RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development

Advanced Science, EarlyView.
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao, Tianxiang Tang, Bowen Wang, Shengfei He, Yue Zhang, Li Dong, Bo Xu, Ying Liu, Ping Zhu, Rui Guo   +9 more
wiley   +1 more source

Age‐ and sex‐specific normative values of bone mineral density in the adult glenoid

Journal of Orthopaedic Research, Volume 41, Issue 2, Page 263-270, February 2023., 2023
Abstract The objective of this study was to determine the normative bone mineral density (BMD) of cortical and trabecular bone regions in the adult glenoid and its dependence on the subject's age and sex. We analyzed computed tomography (CT) scans of 441 shoulders (310 males, 18–69 years) without any signs of glenohumeral joint pathology.
Pezhman Eghbali, Fabio Becce, Patrick Goetti, Frederic Vauclair, Alain Farron, Philippe Büchler, Dominique Pioletti, Alexandre Terrier   +7 more
wiley   +1 more source