Results 1 to 10 of about 598,361 (241)
PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway
Scientific Reports, 2023 This study aimed to explore the potential role and mechanisms of the partner of NOB1 homolog (PNO1) in osteosarcoma. The expression of PNO1 in tumor and adjacent tissue samples was examined using western blotting.
Long Fang +4 more
doaj +1 more source
Cancer Cell International, 2022 Purpose Nectin-4 is specifically up-regulated in various tumors, exert crucial effects on tumor occurrence and development. Nevertheless, the role and molecular mechanism of Nectin-4 in osteosarcoma (OS) are rarely studied.
Yongheng Liu +11 more
doaj +1 more source
Cell Death Discovery, 2023 m6A is an important RNA methylation in progression of various human cancers. As the m6A reader protein, YTHDF1 is reported to accelerate m6A-modified mRNAs translation in cytoplasm.
Yanan Zhu +8 more
doaj +1 more source
Non-coding RNAs in necroptosis, pyroptosis and ferroptosis in cancer metastasis
Cell Death Discovery, 2021 Distant metastasis is the main cause of death for cancer patients. Recently, the newly discovered programmed cell death includes necroptosis, pyroptosis, and ferroptosis, which possesses an important role in the process of tumor metastasis.
Yan Liu +7 more
doaj +1 more source
p62 Overexpression Promotes Bone Metastasis of Lung Adenocarcinoma out of LC3-Dependent Autophagy
Frontiers in Oncology, 2021 p62 protein has been implicated in bone metastasis and is a multifunctional adaptor protein usually correlated with autophagy. Herein, we investigated p62 expression and its prognostic significance in bone metastasis of lung adenocarcinoma, and analyzed ...
Dongqi Li +6 more
doaj +1 more source
A clinical case of multiple primary cancers in a carrier of rare SDK2 and NOTCH2 gene mutations
Egyptian Journal of Medical Human Genetics, 2021 Background Genetic predisposition is one of the risk factors for the development of multiple primary cancers (MPCs), the frequency of which increases and ranges from 2 to 17%.
Nataliya N. Timoshkina +6 more
doaj +1 more source
Experimental ex-vivo validation of PMMA-based bone cements loaded with magnetic nanoparticles enabling hyperthermia of metastatic bone tumors [PDF]
, 2017 Percutaneous vertebroplasty comprises the injection of Polymethylmethacrylate (PMMA) bone cement into vertebrae and can be used for the treatment of compression fractures of vertebrae.
Crevecoeur, Guillaume +5 more
core +3 more sources
Dedifferentiated giant-cell tumor of bone with an undifferentiated round cell mesenchymal component
Rare Tumors, 2014 The dedifferentiated giant-cell tumor of the bone is a very rare variant of the giant-cell tumor (GCT). We report the clinical, radiographic and histological findings of a dedifferentiated GCT in which the dedifferentiated component consisted of small ...
Eréndira G. Estrada-Villaseñor +4 more
doaj +1 more source
Marjolin's Tumor Complicating Chronic Periprosthetic Infection of a Total Knee Arthroplasty [PDF]
Journal of Bone and Joint Infection, 2019 Marjolin's tumor is a term used to describe a malignancy developing in the setting of a chronic wound, infection, or other tissue subject to chronic inflammatory changes.
T. Horan +3 more
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Cell Death and Disease, 2021 Bone metastasis is one of the most serious complications in lung cancer patients. MicroRNAs (miRNAs) play important roles in tumour development, progression and metastasis.
Lei Han +11 more
doaj +1 more source