Results 91 to 100 of about 28,056 (263)

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Advanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Luis M. Arellano, Tommaso Battisti, Gloria Garcia‐Ortega, Neus Lozano, Alberto Bianco, Kostas Kostarelos, Laura Ballerini, Giada Cellot   +10 more
wiley   +1 more source

Ductile B2 Intermetallics‐Driven Strength‐Ductility Synergy in Heterolaminated Multi‐Principal Element Alloys

Advanced Science, EarlyView.
Intrinsic phase toughening transforms a brittle B2 intermetallic into a plastically deformable, load‐bearing phase, while a heterogeneous laminated architecture suppresses strain localization and interface cracking. The synergy between ductile intermetallics and mesoscale heterogeneity establishes a general design strategy for breaking the long ...
Lu Yang, Feilong Jiang, Qiming Zhuang, Dingshan Liang, Jiasi Luo, Kangjie Chu, Junhua Luan, Zengbao Jiao, Robert O. Ritchie, Fuzeng Ren   +9 more
wiley   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Surgical treatment of nonunion of the lateral humeral condyle in children using combined methods of bone grafting and the Ilizarov fixation

Гений oртопедии
Introduction Elbow trauma is common accounting for 40-50 % of all musculoskeletal injuries in children. From them, lateral condyle fractures are the second most common fractures in the pediatric elbow with complications ranging from 3.3 to 54.8 %. The
Payzulla U. Urinboev, Sharof M. Davirov, Ikrom P. Urinbaev   +2 more
doaj   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam, Yong Kwon Chae, Seoung‐Jin Hong, Younggen Lee, Dongwook Yang, Byunggi Kim, Sang Wook Kang, Young‐Jin Kim   +7 more
wiley   +1 more source

Towards Advanced Intelligent and Perceptive Soft Grippers

Advanced Intelligent Systems, EarlyView.
Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim, Hayeon Shin, Seik Park, Changbeom Shim, Seonggun Joe   +4 more
wiley   +1 more source

Field‐Programable Dynamics in a Soft Magnetic Actuator Enabling True Random Number Generation and Reservoir Computing

Advanced Intelligent Systems, EarlyView.
Complex dynamics, often avoided in electromechanical design, can enhance soft robotics. We develop durable magnetic soft actuators operating in tunable dynamic regimes, enabling random number generation, stochastic computing, and time‐series prediction.
Eduardo Sergio Oliveros‐Mata, Oleksandr V. Pylypovskyi, Eleonora Raimondo, Rico Illing, Yevhen Zabila, Lin Guo, Guannan Mu, Mónica Navarro López, Xu Wang, Georgios Tzortzinis, Angelos Filippatos, Gilbert Santiago Cañón Bermúdez, Francesca Garescì, Giovanni Finocchio, Denys Makarov   +14 more
wiley   +1 more source

Soft Active Electromyography Interface for Machine Learning‐Enabled Silent Speech Recognition

Advanced Intelligent Systems, EarlyView.
A soft, hand‐worn electromyography interface enables intent‐driven silent speech recognition without continuous facial attachment. The device integrates liquid‐metal interconnects, a transparent flexible circuit, and elastomer encapsulation with a fingertip electrode that contacts perioral muscles only on demand.
Yuta Kurotaki, Shusuke Yamakoshi, Reitaro Yoshida, Yutaka Isoda, Tamami Takano, Yuji Isano, Yusuke Miyake, Kentaro Kuribayashi, Hiroki Ota   +8 more
wiley   +1 more source

Pediatric Mandibular Fracture Management: Intraoperative Thermoplastic Splint Fabrication and Circummandibular Wires, without Maxillomandibular Fixation

Plastic and Reconstructive Surgery, Global Open
Summary:. Management of mandibular fractures often involves the use of maxillomandibular fixation (MMF) to attain immobility of the fractured segments. This can be used as a primary treatment modality or as an adjunct in fracture management.
Jack D. Sudduth, MD, MS, Richard Byrd, DDS, Jessica L. Marquez, BA, Catherine H. Bautista, BS, Joanna Chen, BA, Andrea Battistini, MD, Duane K. Yamashiro, DDS, MS, Barbu Gociman, MD, PhD   +7 more
doaj   +1 more source