Results 81 to 90 of about 28,056 (263)

Mandibular posterior bone anchorage technique using steel wire: a retrospective descriptive study on dental movements and clinical tolerance

open access: yesJournal of Oral Medicine and Oral Surgery
Introduction: In 2015, a new technique for posterior mandibular bone anchorage, termed “Abalakov”, was introduced. This technique enables the distalization of mandibular teeth and the entire arch as needed, utilizing a single steel wire anchored to the ...
Grzelczyk Lucie   +4 more
doaj   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

open access: yesAdvanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng   +19 more
wiley   +1 more source

Intramedullary Wire-Guided Bone Transport of the Ulna: A Case Report

open access: yesCureus
Diaphyseal bone defects of the forearm may arise from high-energy trauma, the surgical excision of devitalised or contaminated bone in open fractures, tumour resection, or extensive debridement for infected non-unions. These defects pose a considerable challenge in trauma and orthopaedic surgery due to the complexity of restoring limb function and ...
Badrol Hisham, Mohammad Fakhriy   +3 more
openaire   +3 more sources

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba   +25 more
wiley   +1 more source

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia   +9 more
wiley   +1 more source

Evaluation of the effect of osteosynthesis wires on the structural reorganization of metaepiphyseal cartilage (an experimental and morphological study)

open access: yesГений oртопедии
Introduction Premature arrest of bone growth is the most common complication of bone fractures at the growth plate level. The purpose of the work was to evaluate the structural reorganization of metaepiphyseal cartilage following its direct injury ...
Anatoly A. Korobeinikov   +4 more
doaj   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

open access: yesAdvanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky   +15 more
wiley   +1 more source

Chemically Gradient Ordered Nanodomains Enable Large Tensile Ductility in Gigapascal Lightweight Refractory High‐Entropy Alloys

open access: yesAdvanced Science, EarlyView.
A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang   +3 more
wiley   +1 more source

Elastic Intramedullary Nail versus K. Wires in Management of Pediatric Both-Bone Forearm Fractures [PDF]

open access: yesAl-Azhar International Medical Journal
Background: Diaphyseal fractures of both bones in the forearms are amongst the most prevalent fractures in children, making up anywhere from 13 to 40 percent of all pediatric fractures.Aim and objectives: To evaluate pediatric diaphyseal fracture ...
doaj   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He   +9 more
wiley   +1 more source

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