Results 171 to 180 of about 28,897 (262)

Surgical Management of Exceptionally Severe Cubitus Varus Deformity in Osteogenesis Imperfecta: A Case Report. [PDF]

J Orthop Case Rep
Wako M, Hagino T, Ichikawa J, Hagino T, Haro H.   +4 more
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Retrograde Nailing of an Unstable Distal-Third Femoral Shaft Fracture Using Pure Indirect Reduction: A Case Report in Osteoporotic Bone. [PDF]

J Orthop Case Rep
Rajadurai OJW, Kumar MS, Purushothaman K, Parasarann G, Abraham A, Kanna PD.   +5 more
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Inferior Pole Scaphoid Nonunion in a 12-Year-Old Boy: Lessons on Compliance, Follow-Up, and Surgical Salvage-A Case Report. [PDF]

Reports (MDPI)
Alrashed AH, Alamer AA, Alhassan MJ, Alkhars AM, Althabit FM, Alhussain MA, Alkhars AF.   +6 more
europepmc   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source

Repositioned Kirschner Wires as a Temporary Metaphyseal Block to Prevent Articular Extension During Opening-Wedge High Tibial Osteotomy. [PDF]

Arthrosc Tech
García Bordes L, Cuscó Segarra X, Álvarez Díaz P, Seijas Vázquez R, Barastegui Fernández D, Velasco Alcalde P, Cugat Bertomeu R.   +6 more
europepmc   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

A 4-Anchor Suture Tape Internal Bracing Technique for Ligamentous Perilunate Injuries. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Hays T, Johnson T, Brown B.
europepmc   +1 more source

Additional lateral meniscus centralization reduces residual anterolateral rotatory instability after anterior cruciate ligament reconstruction and lateral meniscus repair

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to examine the effects of lateral meniscus (LM) centralization on anterolateral rotational stability in patients with anterior cruciate ligament (ACL) and LM injuries. The hypothesis was that performing LM repair and centralization on knees with LM lesions would control anterolateral rotatory instability (ALRI ...
Ryota Seki, Tomomasa Nakamura, Nobutake Ozeki, Yusuke Nakagawa, Mai Katakura, Takashi Hoshino, Masaki Amemiya, Aritoshi Yoshihara, Hideyuki Koga   +8 more
wiley   +1 more source