Results 101 to 110 of about 970,203 (307)

Primary lymphomas of bones and soft tissues: comparative assessment of treatment results

open access: yesТерапевтический архив, 2012
Aim. To evaluate the efficiency of intensive polychemotherapy (PCT) in adult patients having diffuse large B-cell lymphoma (DLBL) of bones and soft tissues with and without poor prognostic factors (PPF). Subjects and methods. Out of 58 enrolled patients,
A K Morozova   +16 more
doaj  

Obesity impact on bones and joints health

open access: yesJournal of Education, Health and Sport
Introduction and objective Obesity, characterized by excessive fat accumulation, poses significant health risks. The WHO classifies overweight as a BMI of 25 to
Waldemar Mrugała   +9 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Dog Breeding Among the Population of the Town of Beryozov in the XVI–XIX Centuries (based on the results of the study of the osteological collection)

open access: yesАрхеология евразийских степей
The paper considers the osteological collection of late medieval dogs from the excavations of the Beryozov hillfort of the XVI–XIX centuries. In the frozen cultural layer, numerous bone remains (more than 547 items), including almost complete skeletons ...
Tatiana V. Lobanova   +2 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Correction of destructive changes in connective tissues of different organs during chronic nitrate and fluoride intoxication by nanosized silica oxide

open access: yesJournal of Education, Health and Sport, 2019
This experiment carried on 35 white Wistar rats aimed at studying the markers of connective tissue destruction during chronic nitrate-fluoride intoxication and its correction by nanosized silica oxide.
O. Ye. Akimov   +2 more
doaj  

GROWTH ANALYSIS AND ASSESSMENT OF PIG’S BIOLOGICAL MAXIMUM [PDF]

open access: yesPoljoprivreda, 2010
The aim of this study was to determine a mathematical model which can be used to describe the growth of domestic animals in an attempt to predict the optimal time of slaughter/weight or the development of body parts or tissues and estimate the biological
Dragutin Vincek
doaj  

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