Results 71 to 80 of about 468,824 (233)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Didatic approach of ultrasonographic examination for evaluation of the carpal joint in horses

Ciência Rural, 2017
: The carpus is a complex articulation, which is often involved in injuries in equine athletes. The objective of this study was to suggest a didactic approach for ultrasonography training for the examination of the carpal joint in horses.
Maria Cristina Ferrarini Nunes Soares Hage, Mariana Sachi Invernizzi, Gabriela Monaldo Corrá Bellegard, Renata Gebara Sampaio Dória, Silke Verena Schwarzbach, Vanessa Junko Yamaguti Miada   +5 more
doaj   +1 more source

Guia de bones pràctiques

, 2016
Fitxa divulgativa del Banc d'Experiències i Bones ...
Banc d'Experiències i Bones Pràctiques, Gerència d'Àrea de Drets Socials, Salut, Cooperació i Comunitat   +1 more
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Fermented Rapeseed Meal as a Dietary Intervention to Improve Mineral Utilization and Bone Health in Weaned Piglets

Animals
This study examined the effects of incorporating fermented rapeseed meal (FRSM) into the diet of newly weaned piglets on mineral digestibility and bone health.
Anna Czech, Katarzyna Woś, Karol Pachciński, Siemowit Muszyński, Michał Świetlicki, Ewa Tomaszewska   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Primary lymphomas of bones and soft tissues: comparative assessment of treatment results

Терапевтический архив, 2012
Aim. To evaluate the efficiency of intensive polychemotherapy (PCT) in adult patients having diffuse large B-cell lymphoma (DLBL) of bones and soft tissues with and without poor prognostic factors (PPF). Subjects and methods. Out of 58 enrolled patients,
A K Morozova, E E Zvonkov, V E Mamonov, A M Kremenetskaia, S K Kravchenko, M A Tseĭtlina, D L Stroiakovskiĭ, E A Bariakh, A U Magomedova, T N Obukhova, K D Kaplanov, L A Pustovoĭt, A I Lukina, É G Gemdzhian, E K Egorova, M Iu Pen'kov4, A I Vorob'ev   +16 more
doaj  

Obesity impact on bones and joints health

Journal of Education, Health and Sport
Introduction and objective Obesity, characterized by excessive fat accumulation, poses significant health risks. The WHO classifies overweight as a BMI of 25 to
Waldemar Mrugała, Bartosz Skierkowski, Sebastian Mrugała, Michał Muciek, Jakub Kawka, Kinga Filipek, Filip Czyżewski, Katarzyna Baranowska, Alicja Baranowska, Natalia Zalewska   +9 more
doaj   +1 more source