Results 181 to 190 of about 3,884,723 (284)

Effects of integrating self-efficacy strategies into multi-joint resistance exercise for overweight and obese older adults: A randomized controlled trial. [PDF]

PLoS One
Kanlayawut O, Maphong R, Wongpipit W, Kritpet T.   +3 more
europepmc   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Effects of Caffeine and <i>Rhodiola rosea</i>, Alone and Combined, on DanceSport-Specific Jive Performance: A Randomized, Blinded, Placebo-Controlled Trial. [PDF]

Nutrients
Dai X, Liu M, Liu S, Tang J, Yu L, Liu C, Yu J, Li X, Chou T, Liu C.   +9 more
europepmc   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Dynamic pupillometry in patients with visible optic disc drusen: a cross-sectional study. [PDF]

BMC Ophthalmol
Yıldırım I, Karakaya C, Öztekin A.
europepmc   +1 more source

Some inequalities of Bonferroni--Galambos type

Let A1, A2,..., An be events of a given probability space, and [nu]n be the number of events among them which occur. Some estimates are given of P([nu]n [greater-or-equal, slanted] j) by means of the binomial moments.binomial moments Bonferroni--Galambos
Xu, Yuan, Tan, Xiaodong
core  

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Functional Characterization and Transcriptional Regulation of Olive Tocopherol Methyltransferase Responsible for the Vitamin E Content of Virgin Olive Oil. [PDF]

J Agric Food Chem
Muñoz-Ocaña C, Narváez I, Sicardo MD, Hernández ML, Moreda W, Martínez-Rivas JM.   +5 more
europepmc   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Information Quality and Semantic Stability of AI Chatbot Responses to Complete Denture Questions: A Turkish-English Benchmarking Study. [PDF]

Healthcare (Basel)
Coşkun S, Karaman FN, Uytun HA, Coşkun Akar G.   +3 more
europepmc   +1 more source