Results 51 to 60 of about 3,884,723 (284)

Logicome Profiler: Exhaustive detection of statistically significant logic relationships from comparative omics data.

open access: yesPLoS ONE, 2020
Logic relationship analysis is a data mining method that comprehensively detects item triplets that satisfy logic relationships from a binary matrix dataset, such as an ortholog table in comparative genomics.
Tsukasa Fukunaga, Wataru Iwasaki
doaj   +1 more source

Active ageing profiles according to personal and contextual characteristics (t-test with post-hoc Bonferroni correction for means comparisons).

open access: yes, 2022
Active ageing profiles according to personal and contextual characteristics (t-test with post-hoc Bonferroni correction for means comparisons).
Carmen Rodriguez-Blazquez (839905)   +10 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Reconfiguration of Dynamic Functional Connectivity States in Patients With Lifelong Premature Ejaculation

open access: yesFrontiers in Neuroscience, 2021
Purpose: Neuroimaging has demonstrated altered static functional connectivity in patients with premature ejaculation (PE), while studies examining dynamic changes in spontaneous brain activity in PE patients are still lacking.
Jiaming Lu   +13 more
doaj   +1 more source

Multiattribute Decision-Making Method with Intuitionistic Fuzzy Archimedean Bonferroni Means [PDF]

open access: yesMathematical Problems in Engineering, 2021
The Bonferroni mean (BM) can portray the inter-relationships among the arguments, which is based on algebraic norm. Archimedean norm is the generalization of algebraic norm. In this work, the intuitionistic fuzzy (IF) BMs on the basis of the Archimedean norm are investigated, including the Archimedean norm-based IF arithmetic BM (AN-IFABM) and the ...
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Another Generalized Transmuted family of distributions:Properties and Applications

open access: yesAustrian Journal of Statistics, 2016
We introduce and study general mathematical properties of a new generator of continuous distributions with two extra parameters called the Generalized transmuted family of distributions. We present some special models.
Faton Merovci   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A New Lifetime Distribution with Decreasing and Upside-Down Bathtub-Shaped Hazard Rate Function

open access: yesStatistica, 2020
We introduce a new lifetime distribution, called the alpha-power transformed Lomax (APTL) distribution which generalizes the Lomax distribution to provide better fits than the Lomax distribution and some of its known generalizations.
Sanku Dey   +4 more
doaj   +1 more source

In Search for the Genetic Basis of Quality of Life in Healthy Swedish Women--A GWAS Study Using the iCOGS Custom Genotyping Array. [PDF]

open access: yesPLoS ONE, 2015
Quality of life (QoL) is increasingly measured in both research and clinical practice. QoL-assessments are built on a long, empirically-based, and stringent approach. There is ample evidence that QoL is, in part, heritable.
Dounya Schoormans   +7 more
doaj   +1 more source

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