Results 61 to 70 of about 3,884,723 (284)
, 2021 Thinking right requires means or tools of thinking. Thismeans is certain, so scientific activity will not be maximized withoutthe means of scientific thinking.
Iswanto, Juli; North Sumatra State Islamic University
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Wear and Corrosion Behavior of HVOF-Sprayed WC-CoCr Coatings on Al Alloys
, 2010 WC-CoCr coatings were HVOF-sprayed onto an AA6082T6 substrate. Thickness values between 50 and150 lm were produced by stepwise increase of the number of torch scans. This increase made thecoatings not only thicker but also denser.
BOLELLI, Giovanni +7 more
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FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Depth-sensing indentation for assessing the mechanical properties ofcold-sprayed Ta
, 2010 The stress–strain behaviour of cold-sprayed Ta coatings, deposited onto Al and steel substrates, was studiedby depth-sensing spherical and sharp (Berkovich) indentation testing, and was compared to that of anannealed Ta sheet.
BOLELLI, Giovanni +9 more
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
, 2019 Adjusted means for behaviors, demographics, and health outcomes by behavior profile and Bonferroni test results.
Francine Laden (60940) +10 more
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Multiple-comparison computer program using the bonferroni t statistic [PDF]
, 1980 To ascertain the agreement among laboratories, samples from a single batch of material are analyzed by the different laboratories and results are then compared. A graphical format was designed for presenting the results and for showing which laboratories
Johnson, E. E.
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