Results 91 to 100 of about 7,369 (207)

A novel strain-based bone-fracture healing algorithm is able to predict a range of healing outcomes

Frontiers in Bioengineering and Biotechnology
Fracture healing is a complex process which sometimes results in non-unions, leading to prolonged disability and high morbidity. Traditional methods of optimising fracture treatments, such as in vitro benchtop testing and in vivo randomised controlled ...
George T. Morgan, Lucas Low, Arul Ramasamy, Arul Ramasamy, Arul Ramasamy, Spyros D. Masouros   +5 more
doaj   +1 more source

Warfare, Labor, and Urban Stress: Divergent Health Trajectories in Mongol‐Period Karakorum

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study examines major palaeopathological trends in Mongol‐period Karakorum and incorporates them into the existing body of research in order to deepen our understanding of health and survival, the impacts of conflict and violence on past populations, and the lived experiences of the city's diverse inhabitants within the broader socio ...
Júlia Olive‐Busom, Susanne Reichert, Dunburee Batsukh, Jan Bemmann, Alice Toso   +4 more
wiley   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Standard bone healing stages occur during delayed bone healing, albeit with a different temporal onset and spatial distribution of callus tissues [PDF]

, 2010
Bone healing is considered as a recapitulation of a developmental program initiated at the time of injury. This study tested the hypothesis that in delayed bone healing the regular cascade of healing events, including remodeling of woven to lamellar ...
Peters, Anja, Hannemann, Marion, Duda, Georg N., Bail, Hermann J., Schell, Hanna, Schumann, Tanja, Lienau, Jasmin   +6 more
core  

A critical appraisal of the safety of bedinvetmab (Beransa), a canine antinerve growth factor monoclonal antibody

Australian Veterinary Journal, EarlyView.
Clinical scenario Canine osteoarthritis (OA) is a degenerative joint disease and is one of the most common chronic conditions in dogs and other species. The management of OA remains a longstanding focus in veterinary medicine. Traditionally, nonsteroidal anti‐inflammatory drugs (NSAIDs) have been the first‐line treatment option for canine OA. Recently,
X Yang, P Macarthur
wiley   +1 more source

Partial amputation regrowth of P4 distal digit in an eastern grey kangaroo (Macropus giganteus): a case report

Australian Veterinary Journal, EarlyView.
This case report describes distal regrowth of the fourth hind digit (P4) following traumatic autoamputation in a young adult eastern grey kangaroo (Macropus giganteus). Injury to P4 is generally considered to carry a poor prognosis due to its critical role in weight‐bearing and propulsion during hopping.
L Cummins, G Cummins, J Clough, A Shen
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Unexpected Promotion of Bone Regeneration by Inhibition of BMPR1A‐Mediated BMP Signalling

Cell Proliferation, EarlyView.
BMPR1A downregulation reduces ID1, releases TCF3 to activate GNG4‐PI3K‐AKT signalling, thereby promoting OPC proliferation and bone regeneration. ABSTRACT Bone morphogenetic protein (BMP) signalling plays a pivotal role in bone regeneration by regulating osteoprogenitor cell (OPC) function, and BMPs have been widely used in clinical treatment. However,
Zihao Zhou, Yun Zhai, Xiaochen Liu, Jiaojiao Shao, Jiani Zhou, Zhaoyang Li, Jiale He, Shuxian Lin, Qi Zhang   +8 more
wiley   +1 more source

Marxism and Decolonizing Praxis: From Decolonial Misinterpretations to Marxist Contributions

Development and Change, EarlyView.
ABSTRACT This article intervenes in postcolonial and decolonial critiques that portray Karl Marx and Marxism as intrinsically Eurocentric and inattentive to race, colonialism and non‐European revolutionary agency. It argues that such critiques often rely on selective, historically limited interpretations that overlook Marx's later writings, in which he
Ana Cecilia Dinerstein
wiley   +1 more source

Long‐term outcome of a non‐reducible congenital atlanto‐occipital subluxation in a warmblood foal

Equine Veterinary Education, EarlyView.
Summary An 11‐day‐old warmblood colt was referred to the Large Animal Teaching Hospital, University of Copenhagen, for further investigation of a stiff neck and lateral deviation of the poll, with suspicion of a congenital cervical vertebral abnormality.
D. M. T. Adler, S. Hansen, L. Rasmussen, S. Jacobsen   +3 more
wiley   +1 more source