Results 91 to 100 of about 7,349 (211)
Is callus formation optimised for fracture stability? A computational study
, 2006 Aims\ud \ud Fractures that are not rigidly fixed heal via the formation of a fibro-cartilaginous callus, which is progressively converted to bone. We examine the hypothesis that callus morphology is optimal to achieve a defined limiting stiffness of the
Wullschleger, Martin E. +6 more
core
A novel strain-based bone-fracture healing algorithm is able to predict a range of healing outcomes
Frontiers in Bioengineering and BiotechnologyFracture healing is a complex process which sometimes results in non-unions, leading to prolonged disability and high morbidity. Traditional methods of optimising fracture treatments, such as in vitro benchtop testing and in vivo randomised controlled ...
George T. Morgan +5 more
doaj +1 more source
Unexpected Promotion of Bone Regeneration by Inhibition of BMPR1A‐Mediated BMP Signalling
Cell Proliferation, EarlyView.BMPR1A downregulation reduces ID1, releases TCF3 to activate GNG4‐PI3K‐AKT signalling, thereby promoting OPC proliferation and bone regeneration. ABSTRACT Bone morphogenetic protein (BMP) signalling plays a pivotal role in bone regeneration by regulating osteoprogenitor cell (OPC) function, and BMPs have been widely used in clinical treatment. However,
Zihao Zhou +8 more
wiley +1 more source
, 2009 Tracking tissue deformation is often hampered by material inhomogeneity, so local measurements tend to be insufficient thus lending to the necessity of full-field optical measurements.
Kohles, Sean S., Kim, Wangdo
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An unusual presentation of osteochondrosis in the elbows and tarsi of a Friesian colt
Equine Veterinary Education, EarlyView.Summary This case report describes the clinical, diagnostic imaging results and post‐mortem findings in a foal that underwent reassessment following surgical management of angular limb deformities (ALD) and acute onset of gait abnormalities. Upon presentation, the foal showed an abnormal stiff gait characterised by bilateral medial limb collapse during
A. Torrent‐Crosa +3 more
wiley +1 more source
Standard bone healing stages occur during delayed bone healing, albeit with a different temporal onset and spatial distribution of callus tissues [PDF]
, 2010 Bone healing is considered as a recapitulation of a developmental program initiated at the time of injury. This study tested the hypothesis that in delayed bone healing the regular cascade of healing events, including remodeling of woven to lamellar ...
Peters, Anja +6 more
core
, 2012 SummaryIntroductionClosed reduction of secondary displacements of distal metaphyseal radius fractures is an easy procedure only when performed within the first ten to fifteen days post-trauma, prior to the occurrence of malunion.
Boullet, F. +3 more
core +1 more source
Long‐term outcome of a non‐reducible congenital atlanto‐occipital subluxation in a warmblood foal
Equine Veterinary Education, EarlyView.Summary An 11‐day‐old warmblood colt was referred to the Large Animal Teaching Hospital, University of Copenhagen, for further investigation of a stiff neck and lateral deviation of the poll, with suspicion of a congenital cervical vertebral abnormality.
D. M. T. Adler +3 more
wiley +1 more source
MANAGEMENT OF NONUNION OF FRACTURES BY DISTRACTION WITH CORRECTION OF ANGULATION AND SHORTENING
, 1996 We present a series of ten hypertrophic nonunions in which bony alignment and length were restored and union induced by external fixation and callus distraction.
M. Saleh, S. Royston
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The FEBS Journal, EarlyView.Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki +4 more
wiley +1 more source