Results 81 to 90 of about 11,687 (227)
Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies
VIEW, EarlyView.This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li +5 more
wiley +1 more source
Mechanoregulation of bone remodeling and healing as inspiration for self-repair in materials
, 2019 The material bone has attracted the attention of material scientists due to its fracture resistance and ability to self-repair. A mechanoregulated exchange of damaged bone using newly synthesized material avoids the accumulation of fatigue damage.
Eberl, C., Fratzl, P., Weinkamer, R.
core +1 more source
Journal of the Royal Anthropological Institute, EarlyView.While death remains a popular topic for anthropology, relatively few ethnographic accounts consider the modern bureaucratic processes accompanying it. One such process is public health autopsy, which scholars have largely taken for granted. Existing analysis has regarded it as a form of ‘cultural brokering’ and autopsy reluctance in communities is seen,
David M.R. Orr
wiley +1 more source
Australian Veterinary Journal, EarlyView.Clinical scenario Canine osteoarthritis (OA) is a degenerative joint disease and is one of the most common chronic conditions in dogs and other species. The management of OA remains a longstanding focus in veterinary medicine. Traditionally, nonsteroidal anti‐inflammatory drugs (NSAIDs) have been the first‐line treatment option for canine OA. Recently,
X Yang, P Macarthur
wiley +1 more source
Case of Monostotic Fibrous Dysplasia in the hand [PDF]
, 2002 A case of monostotic fibrous dysplasia in the proximal phalanx of an otherwise healthy, twenty-five year old is discussed. Fibrous dysplasia in the hand is rarely seen. Our patient presented with a swelling in his proximal phalanx.
Attard, Gerhardt +2 more
core
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
A novel strain-based bone-fracture healing algorithm is able to predict a range of healing outcomes
Frontiers in Bioengineering and BiotechnologyFracture healing is a complex process which sometimes results in non-unions, leading to prolonged disability and high morbidity. Traditional methods of optimising fracture treatments, such as in vitro benchtop testing and in vivo randomised controlled ...
George T. Morgan +5 more
doaj +1 more source
The Temporal Expression of Adipokines During Spinal Fusion [PDF]
, 2017 Background Context Adipokines are secreted by white adipose tissue and have been associated with fracture healing. Our goal was to report the temporal expression of adipokines during spinal fusion in an established rabbit model.
Bertone, Alicia L. +5 more
core +1 more source
The history, evolution and basic science of osteotomy techniques. [PDF]
, 2017 Osteotomy techniques date back to Hippocrates circa 415 BC (Jones Hippocrates collected works I, Harvard University Press, Cambridge, 2006; Brorson in Clin Orthop Relat Res 467(7):1907-1914, 2009).
Dabis, J +4 more
core +2 more sources
Clinical Endocrinology, EarlyView.ABSTRACT Context Placental calcium (Ca2+) transport is essential for foetal bone mineralisation and development, as well as for Ca2+ homoeostasis. Rare mutations in transient receptor potential vanilloid (TRPV) 6 of the infant cause insufficient maternal‐foetal Ca2+ transport through the placenta.
Teodora Grigore +6 more
wiley +1 more source