Results 51 to 60 of about 7,066 (201)

High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model. [PDF]

open access: yesPLoS ONE, 2017
Small animal studies have demonstrated significant high-dose recombinant parathyroid hormone1-34 (rPTH1-34) effects on intercalary allograft healing. Towards a human adjuvant therapy to decrease non-unions, we evaluated rPTH1-34 safety and efficacy in a ...
Kohei Nishitani   +7 more
doaj   +1 more source

The First Healed Bite Mark and Embedded Tooth in the Snout of a Middle Permian Gorgonopsian (Synapsida: Therapsida)

open access: yesFrontiers in Ecology and Evolution, 2021
Despite their significance for paleobiological interpretations, bite marks have been rarely reported in non-mammalian therapsids (NMT). Here we describe, for the first time, the occurrence of a tooth embedded in the snout of a gorgonopsian.
Julien Benoit   +2 more
doaj   +1 more source

A Bio‐Inspired Perspective on Materials Sustainability

open access: yesAdvanced Materials, EarlyView.
This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier   +2 more
wiley   +1 more source

Modulation of fixation stiffness from flexible to stiff in a rat model of bone healing

open access: yesActa Orthopaedica, 2017
Background and purpose — Constant fixator stiffness for the duration of healing may not provide suitable mechanical conditions for all stages of bone repair.
Nicole Bartnikowski   +8 more
doaj   +1 more source

Accelerated Bone Healing via Electrical Stimulation

open access: yesAdvanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun   +4 more
wiley   +1 more source

Histological Evaluation for the Use of β-Tricalcium Phosphate as a Bone Substitute in Accelerating Bone Healing: An Experimental Study on Rabbits [PDF]

open access: yesAl-Rafidain Dental Journal, 2014
Aims: The present study designed to assess the effects of a bone substitute consisting of β-Tricalcium Phosphate (β-TCP) on acceleration of bone healing of surgically created defects. Materials and Methods: Ten rabbits were included in the study.
Atalla F Rejab   +2 more
doaj   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

open access: yesAdvanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie   +10 more
wiley   +1 more source

Seizure or child abuse?

open access: yesRevista de la Facultad de Medicina Humana, 2021
More child abuse cases are reported in Peru every year; however, there is no official report that describes the actual incidence, especially of the most vulnerable population such as infants.
Consuelo del Rocio Luna Muñoz   +3 more
doaj   +1 more source

Functional Divergence of Plant‐Derived Thaumatin‐Like Protein Genes in Two Closely Related Whitefly Species

open access: yesAdvanced Science, EarlyView.
Two closely related whitefly species, Trialeurodes vaporariorum and Bemisia tabaci, are found to each possess a plant‐derived TLP gene, but with entirely different functions. This finding of functional divergence challenges the notion that HGT genes maintain similar functions across species and shows that they can follow unique evolutionary paths that ...
Yuan Hu   +12 more
wiley   +1 more source

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