Results 51 to 60 of about 11,689 (233)

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Systemic treatment with telmisartan improves femur fracture healing in mice. [PDF]

open access: yesPLoS ONE, 2014
Recent clinical studies indicated that angiotensin receptor blockers (ARBs) would decrease the risk of bone fractures in the elderly populations. There is little known about the role of the ARBs in the process of fracture healing.
Xiong Zhao   +8 more
doaj   +1 more source

Outcome of Early Weight Bearing Cast for the Treatment of Jones Fracture

open access: yesJournal of Bahria University Medical and Dental College, 2023
Objective: To determine the radiological and functional outcome of acute Jones fracture treated conservatively in early weight bearing cast. Study Design and Setting: This study was conducted in Orthopaedic Division Lady Reading Hospital Peshawar.
Faaiz Ali Shah   +3 more
doaj   +1 more source

Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]

open access: yes, 2020
Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina   +10 more
core   +1 more source

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

open access: yesAdvanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren   +10 more
wiley   +1 more source

High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model. [PDF]

open access: yesPLoS ONE, 2017
Small animal studies have demonstrated significant high-dose recombinant parathyroid hormone1-34 (rPTH1-34) effects on intercalary allograft healing. Towards a human adjuvant therapy to decrease non-unions, we evaluated rPTH1-34 safety and efficacy in a ...
Kohei Nishitani   +7 more
doaj   +1 more source

The First Healed Bite Mark and Embedded Tooth in the Snout of a Middle Permian Gorgonopsian (Synapsida: Therapsida)

open access: yesFrontiers in Ecology and Evolution, 2021
Despite their significance for paleobiological interpretations, bite marks have been rarely reported in non-mammalian therapsids (NMT). Here we describe, for the first time, the occurrence of a tooth embedded in the snout of a gorgonopsian.
Julien Benoit   +2 more
doaj   +1 more source

Mechanoregulation of bone remodeling and healing as inspiration for self-repair in materials

open access: yes, 2019
The material bone has attracted the attention of material scientists due to its fracture resistance and ability to self-repair. A mechanoregulated exchange of damaged bone using newly synthesized material avoids the accumulation of fatigue damage.
Eberl, C., Fratzl, P., Weinkamer, R.
core   +1 more source

Co‐Treatment With rhBMP‐2 and Rapamycin Modulates Osteogenesis–Adipogenesis Balance to Enhance Aged Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He   +7 more
wiley   +1 more source

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