Results 31 to 40 of about 7,349 (211)
Vibration therapy as an effective approach to improve bone healing in diabetic rats
Frontiers in Endocrinology, 2022 ObjectiveTo investigate the effects of vibration therapy on fracture healing in diabetic and non-diabetic rats.Methods148 rats underwent fracture surgery and were assigned to four groups: (1) SHAM: weight-matched non-diabetic rats, (2) SHAM+VT: non ...
Maysa S. Campos +10 more
doaj +1 more source
T cells heal bone fractures with help from the gut microbiome
The Journal of Clinical Investigation, 2023 Immune cells play an important functional role in bone fracture healing. Fracture repair is a well-choreographed process that takes approximately 21 days in healthy mice.
Rajeev Aurora, Matthew J. Silva
doaj +1 more source
Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose: To evaluate the effects of food restriction on fracture healing in growing rats. Methods: Sixty-eight male Wistar rats were assigned to two groups: (1) Control and (2) Dietary restriction. After weaning the dietary restricted animals were fed
Iara Inácio Botega +8 more
doaj +1 more source
Nandrolone decanoate appears to increase bone callus formation in young adult rats after a complete femoral fracture [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To evaluate the influence of nandrolone decanoate on fracture healing and bone quality in normal rats. Methods: Male rats were assigned to four groups (n=28/group): Control group consisting of animals without any intervention, Nandrolone ...
Ana Paula Franttini Garcia Moreno Guimarães +4 more
doaj +1 more source
Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair. [PDF]
PLoS ONE, 2015 Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis.
Vanessa Scanlon +6 more
doaj +1 more source
Frontiers in Endocrinology, 2021 BackgroundOsteogenesis imperfecta (OI) type V is a rare form of OI which is often characterized by hyperplastic callus. Misdiagnosis is a possibility due to its rarity and because patients involved are mostly in adolescence, a predisposing age for ...
Ying Deng, Yanan Huo, Jinfeng Li
doaj +1 more source
BMC Musculoskeletal Disorders, 2022 Background To estimate the effects of different intensities of intermittent pneumatic soft-tissue compression on bone defect repair in an animal model. Methods Five mm radial bone defect in length was made in 64 mature New Zealand rabbits and all animals
Weilong Diwu +6 more
doaj +1 more source
Endogenous PTH deficiency impairs fracture healing and impedes the fracture-healing efficacy of exogenous PTH(1-34). [PDF]
PLoS ONE, 2011 Although the capacity of exogenous PTH1-34 to enhance the rate of bone repair is well established in animal models, our understanding of the mechanism(s) whereby PTH induces an anabolic response during skeletal repair remains limited.
Yongxin Ren +7 more
doaj +1 more source
Bone & Joint Research, 2023 Aims: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach to
Jonghoo Sung +7 more
doaj +1 more source
Systemic Administration of Recombinant Irisin Accelerates Fracture Healing in Mice [PDF]
, 2021 To date, pharmacological strategies designed to accelerate bone fracture healing are lacking. We subjected 8-week-old C57BL/6 male mice to closed, transverse, mid-diaphyseal tibial fractures and treated them with intraperitoneal injection of a vehicle or
Lorenzo Sanesi +11 more
core +1 more source