Results 21 to 30 of about 7,349 (211)
JBMR Plus, 2023 GαS, the stimulatory G protein α‐subunit that raises intracellular cAMP levels by activating adenylyl cyclase, plays a vital role in bone development, maintenance, and remodeling. Previously, using transgenic mice overexpressing GαS in osteoblasts (GS‐Tg)
Kathy K Lee +3 more
doaj +2 more sources
High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model. [PDF]
PLoS ONE, 2017 Small animal studies have demonstrated significant high-dose recombinant parathyroid hormone1-34 (rPTH1-34) effects on intercalary allograft healing. Towards a human adjuvant therapy to decrease non-unions, we evaluated rPTH1-34 safety and efficacy in a ...
Kohei Nishitani +7 more
doaj +2 more sources
Monitoring the Progress of Treatment in Fracture Non-Union: The Role of Alkaline Phosphatase and Ultrasonography [PDF]
Revista Brasileira de Ortopedia, 2021 Objective To evaluate the role of serum alkaline phosphatase (ALP) and ultrasonography (USG) in monitoring the progress of treatment in diaphyseal non-unions.
Dhanji S Chaudhary +3 more
doaj +1 more source
Bone Reports, 2022 Endochondral bone formation is an important pathway in fracture healing, involving the formation of a cartilaginous soft callus and the process of cartilage-to-bone transition.
Joe Kodama +4 more
doaj +1 more source
Association of fracture configuration and callus formation with a concentration of proinflammatory cytokines in children with long bone fractures [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. The inflammatory response is of utmost importance in bone healing, but the precise role of cells and cytokines remains unclear. In our study, we examined the as-sociation between interleukin-1β (IL-1β), tumor necrosis fac-tors alpha (TNF ...
Paunović Zoran +11 more
doaj +1 more source
Journal of Orthopaedic Translation, 2022 Background: Bone fracture healing is a postnatal regenerative process in which fibrocartilaginous callus formation and bony callus formation are important. Bony callus formation requires osteoblastic differentiation of MSCs.
Fuxiao Wang +9 more
doaj +1 more source
Association of bone fracture type and degree of callus formation with leptin concentration in children with long bone fractures [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Recent studies indicate that adipokines have an important role in bone physiology and pathology. Recent data indicate that adipokine leptin functions as a regulator of bone growth at multiple levels, systemically and locally.
Paunović Zoran +11 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Fracture healing is a complicated, long-term, and multistage repair process. Intermittent administration of parathyroid hormone (PTH) has been proven effective on intramembranous and endochondral bone formation during the fracture healing process ...
Cheng Ma +5 more
doaj +1 more source
The role of hypertrophic chondrocytes in fracture healing
生物医学转化, 2023 Fracture healing is a multifactorial process. Most fractures are healed by the process of endochondral ossification, involving the formation of a cartilaginous soft callus and the process of cartilage-tobone transition.
Zhu Daoyu, Gao Junjie, Gao Youshui
doaj +1 more source
Whole-body vibration improves fracture healing and bone quality in rats with ovariectomy-induced osteoporosis [PDF]
Acta Cirúrgica Brasileira, 2015 PURPOSE: To investigate the effect of vibration therapy on the bone callus of fractured femurs and the bone quality of intact femurs in ovariectomized rats.
Mariana Maloste Butezloff +4 more
doaj +1 more source