Differences in the biological properties of mesenchymal stromal cells from traumatic temporomandibular joint fibrous and bony ankylosis: a comparative study [PDF]
Animal Cells and Systems, 2021 The aim of this study was to compare the functional characteristics of mesenchymal stromal cells (MSCs) from a sheep model of traumatic temporomandibular joint (TMJ) fibrous and bony ankylosis.
Pei-Pei Zhang +9 more
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Callus formation in bone fractures combined with brain injury in rat [PDF]
Formosan Journal of Surgery, 2017 Objective: The objective of this study was to determine the speed of bony union and the serum levels of biomarkers in the setting of bone fractures combined with brain injury.
Yu-Ping Chen, Hsin-Chin Shih
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Human Mesenchymal Stromal Cell Sheet Enhances Allograft Repair in a Mouse Model [PDF]
Scientific Reports, 2017 To determine whether cell sheets generated with long-term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regeneration as tissue engineered periosteum in a femoral allograft mouse model similar to fresh passaged (
Xifu Shang +8 more
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Fully automated segmentation of callus by micro-CT compared to biomechanics [PDF]
Journal of Orthopaedic Surgery and Research, 2017 Background A high percentage of closed femur fractures have slight comminution. Using micro-CT (μCT), multiple fragment segmentation is much more difficult than segmentation of unfractured or osteotomied bone.
Oliver Bissinger +5 more
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Utility of ultrasound imaging in monitoring fracture healing in rat femur: Comparison with other imaging modalities [PDF]
Bone ReportsObjective: Fractures are common injuries and various imaging modalities are employed to diagnose and monitor bone union. However, the follow-up of fracture healing using ultrasound imaging (US) remains a topic of debate.
Satoshi Inoue +5 more
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Increased Osteoblast GαS Promotes Ossification by Suppressing Cartilage and Enhancing Callus Mineralization During Fracture Repair in Mice [PDF]
JBMR Plus, 2023 GαS, the stimulatory G protein α‐subunit that raises intracellular cAMP levels by activating adenylyl cyclase, plays a vital role in bone development, maintenance, and remodeling. Previously, using transgenic mice overexpressing GαS in osteoblasts (GS‐Tg)
Kathy K Lee +3 more
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High dose teriparatide (rPTH1-34) therapy increases callus volume and enhances radiographic healing at 8-weeks in a massive canine femoral allograft model. [PDF]
PLoS ONE, 2017 Small animal studies have demonstrated significant high-dose recombinant parathyroid hormone1-34 (rPTH1-34) effects on intercalary allograft healing. Towards a human adjuvant therapy to decrease non-unions, we evaluated rPTH1-34 safety and efficacy in a ...
Kohei Nishitani +7 more
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Association of bone fracture type and degree of callus formation with leptin concentration in children with long bone fractures [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Recent studies indicate that adipokines have an important role in bone physiology and pathology. Recent data indicate that adipokine leptin functions as a regulator of bone growth at multiple levels, systemically and locally.
Paunović Zoran +11 more
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Frontiers in Cell and Developmental Biology, 2022 Fracture healing is a complicated, long-term, and multistage repair process. Intermittent administration of parathyroid hormone (PTH) has been proven effective on intramembranous and endochondral bone formation during the fracture healing process ...
Cheng Ma +5 more
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The role of hypertrophic chondrocytes in fracture healing
生物医学转化, 2023 Fracture healing is a multifactorial process. Most fractures are healed by the process of endochondral ossification, involving the formation of a cartilaginous soft callus and the process of cartilage-tobone transition.
Zhu Daoyu, Gao Junjie, Gao Youshui
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