Results 201 to 210 of about 12,408,035 (295)

Canalization as a stabilizing principle of gene regulatory networks: a discrete dynamical systems perspective. [PDF]

NPJ Syst Biol Appl
Kadelka C.
europepmc   +1 more source

Clinicoepidemiologic Profile of Oral Kaposi Sarcoma in People Living With HIV: A Systematic Review and Meta‐Analysis

Head &Neck, EarlyView.
ABSTRACT Background To characterize the clinicoepidemiologic profile of HIV‐associated oral Kaposi sarcoma (OKS) and quantitatively synthesize its frequency, anatomical distribution, and temporal patterns across antiretroviral therapy (ART) eras. Methods Six databases and gray literature were searched.
Ericles Otávio, Rebeca Ferreira Badaró, Daniel Pignatari Mahet Rodrigues, Giselle de Medeiros Silva, José Alcides Almeida de Arruda, Victor Zanetti Drumond, Jefferson R. Tenório, Lucas Alves Jural, Marcela Baraúna Magno, Lucianne Cople Maia, Bruno Augusto Benevenuto de Andrade   +10 more
wiley   +1 more source

Hybrid Computational Modeling with Multi-Level Validation Identifies TK1-VIM as a Robust Therapeutic Pair in Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Monteiro SA, Carvalho LAV, Waghabi MC, Silva FABD.   +3 more
europepmc   +1 more source

“Thinking Out Loud” and “Pivoting on the Fly”—An Empirical Review and Critical Incident Study of How Physicians Engage in Incidental Learning Amidst Complexity

Human Resource Development Quarterly, EarlyView.
ABSTRACT This study explores incidental learning among physicians navigating uncertainty during the COVID‐19 pandemic. Using a constructivist research design, we conducted a literature review of 13 empirical studies on incidental learning in complexity and analyzed critical incident interviews with 12 emergency medicine and intensive care physicians ...
Henriette Lundgren, Karen E. Watkins, Victoria J. Marsick, Dimitrios Papanagnou, Urvashi Vaid   +4 more
wiley   +1 more source

Topological Structure of Epigenetic Forests in Flower Morphogenesis. [PDF]

Bull Math Biol
Cortés-Poza Y, Pérez-Buendía JR.
europepmc   +1 more source

Two‐Dimensional Heterostructures: From Controlled Synthesis to Post‐Moore Device Applications

Information &Functional Materials, EarlyView.
This schematic summarizes four typical configurations of two‐dimensional (2D) heterostructures. It also demonstrates their core applications in high‐performance logic transistors, neuromorphic computing, ultra‐broadband photodetection, and multifunctional integrated devices, visually illustrating the diverse development prospects of 2D heterostructures
Jianing Xie, Zijian Niu, Baihui Zhang, Zhengwei Zhang   +3 more
wiley   +1 more source

MYC-SNHG7-miR-34a-5p Feedback Loop Orchestrates GSDMD-Dependent Pyroptosis in Hepatocellular Carcinoma. [PDF]

Int J Mol Sci
Djidonou HR, Gonçalves LC, Fontinele DO, Silveira DA, Sinigaglia M, Lima JPMS, Mombach JCM, Gupta S.   +7 more
europepmc   +1 more source

Mechanical memory in aging: From adaptive sensing to pathological entrenchment

Interdisciplinary Medicine, EarlyView.
Mechanical memory in aging operates through four temporal tiers, from cytoskeletal remodeling to metabolic reprogramming. Aging disrupts this cascade through three distinct decoupling patterns: sensor degradation, conduction blockade, and execution failure, leading to irreversible pathological entrenchment across multiple organ systems.
Mingyang Huang, Xiaoyu Ma, Ruiqi Gao, Qichen Miao, Guoqing Wang, Ziyuan Liu, Kun Wang, Ming Luo   +7 more
wiley   +1 more source

Modeling of gene regulatory networks: an annotated glossary. [PDF]

Trends Plant Sci
Singh Yadav A, Russell NJ, Hernández AI, Petlewski AR, Johnson AR, Grinage AD, Banuna B, Guan CJ, Mahood EH, Younkin GC, Thomas HR, Phillips HR, Harline K, Flasco M, Miller MB, Scinto-Madonich NJ, Szeluga NM, Mendoza PN, Formosa-Jordan P, Roeder AHK.   +19 more
europepmc   +1 more source

Functional Imaging for Identification of Functionally Critical Brain Regions to Spare in Glioma Radiation Therapy Planning: A Systematic Review

Journal of Medical Radiation Sciences, EarlyView.
This review highlights the role of functional imaging in sparing cognitive brain regions during glioma radiotherapy. It shows promising dose reduction without compromising target coverage, but evidence remains limited, requiring standardisation and prospective validation.
Li Wen Yeo, John T. Ryan
wiley   +1 more source