Results 1 to 10 of about 22,279 (116)
Boolean-network simplification and rule fitting to unravel chemotherapy resistance in non-small cell lung cancer. [PDF]
PLoS ONEBoolean networks are powerful frameworks for capturing the logic of gene-regulatory circuits, yet their combinatorial explosion hampers exhaustive analyses.
Alonso Espinoza +2 more
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Node and edge control strategy identification via trap spaces in Boolean networks [PDF]
BMC BioinformaticsBackground The study of control mechanisms of biological systems allows for interesting applications in bioengineering and medicine, for instance in cell reprogramming or drug target identification.
Laura Cifuentes-Fontanals +2 more
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Robust Stabilization of Impulsive Boolean Control Networks with Function Perturbation
Mathematics, 2022 This paper studies the robust stabilization of impulsive Boolean control networks (IBCNs) with function perturbation. A Boolean control network (BCN) with a state-dependent impulsive sequence is converted to an equivalent BCN by the semi-tensor product ...
Qilong Sun, Haitao Li
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Boolean network model predicts knockout mutant phenotypes of fission yeast. [PDF]
PLoS ONE, 2013 Boolean networks (ornetworks of switches) are extremely simple mathematical models of biochemical signaling networks. Under certain circumstances, Boolean networks, despite their simplicity, are capable of predicting dynamical activation patterns of gene
Maria I Davidich, Stefan Bornholdt
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Conversion between Logic and Algebraic Expressions of Boolean Control Networks
Applied Sciences, 2020 The conversion between logic and algebraic expressions of Boolean control networks plays a worthy role in the analysis and design of digital circuits. In this paper, for a single Boolean function, a direct conversion between the minterm canonical form ...
Cailu Wang, Yuegang Tao
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Scientific Reports, 2022 The cell division cycle is regulated by a complex network of interacting genes and proteins. The control system has been modeled in many ways, from qualitative Boolean switching-networks to quantitative differential equations and highly detailed ...
Teeraphan Laomettachit +2 more
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Boolean model of the gene regulatory network of Pseudomonas aeruginosa CCBH4851
Frontiers in Microbiology, 2023 IntroductionPseudomonas aeruginosa infections are one of the leading causes of death in immunocompromised patients with cystic fibrosis, diabetes, and lung diseases such as pneumonia and bronchiectasis. Furthermore, P.
Márcia da Silva Chagas +3 more
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Frontiers in Physiology, 2020 The molecular regulatory network (MRN) within a cell determines cellular states and transitions between them. Thus, modeling of MRNs is crucial, but this usually requires extensive analysis of time-series measurements, which is extremely difficult to ...
Sang-Mok Choo +2 more
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Control in Boolean Networks With Model Checking
Frontiers in Applied Mathematics and Statistics, 2022 Understanding control mechanisms in biological systems plays a crucial role in important applications, for instance in cell reprogramming. Boolean modeling allows the identification of possible efficient strategies, helping to reduce the usually high and
Laura Cifuentes-Fontanals +3 more
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Robustness and backbone motif of a cancer network regulated by miR-17-92 cluster during the G1/S transition. [PDF]
PLoS ONE, 2013 Based on interactions among transcription factors, oncogenes, tumor suppressors and microRNAs, a Boolean model of cancer network regulated by miR-17-92 cluster is constructed, and the network is associated with the control of G1/S transition in the ...
Lijian Yang +8 more
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