Results 1 to 10 of about 144,278 (138)

The power of Boolean implication networks [PDF]

open access: yesFrontiers in Physiology, 2012
Human diseases have been investigated in the context of single genes as well as complex networks of genes. Though single gene approaches have been extremely successful in the past, most human diseases are complex and better characterized by multiple ...
Debashis eSahoo
doaj   +3 more sources

Therapeutic target discovery using Boolean network attractors: improvements of kali [PDF]

open access: yesRoyal Society Open Science, 2018
In a previous article, an algorithm for identifying therapeutic targets in Boolean networks modelling pathological mechanisms was introduced. In the present article, the improvements made on this algorithm, named kali, are described.
Arnaud Poret, Carito Guziolowski
doaj   +4 more sources

Concepts in Boolean network modeling: What do they all mean?

open access: yesComputational and Structural Biotechnology Journal, 2020
Boolean network models are one of the simplest models to study complex dynamic behavior in biological systems. They can be applied to unravel the mechanisms regulating the properties of the system or to identify promising intervention targets.
Julian D. Schwab   +4 more
doaj   +3 more sources

The Dynamics of Canalizing Boolean Networks

open access: yesComplexity, 2020
Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks.
Elijah Paul   +3 more
doaj   +6 more sources

Quotients of Probabilistic Boolean Networks [PDF]

open access: yesIEEE Transactions on Automatic Control, 2022
A probabilistic Boolean network (PBN) is a discrete-time system composed of a collection of Boolean networks between which the PBN switches in a stochastic manner. This paper focuses on the study of quotients of PBNs. Given a PBN and an equivalence relation on its state set, we consider a probabilistic transition system that is generated by the PBN ...
Rui Li 0007   +2 more
openaire   +2 more sources

Reducing Boolean Networks with Backward Boolean Equivalence [PDF]

open access: yes, 2021
Boolean Networks (BNs) are established models to qualitatively describe biological systems. The analysis of BNs might be infeasible for medium to large BNs due to the state-space explosion problem. We propose a novel reduction technique called \emph{Backward Boolean Equivalence} (BBE), which preserves some properties of interest of BNs.
Georgios Argyris   +4 more
openaire   +4 more sources

Random Networks with Quantum Boolean Functions

open access: yesMathematics, 2021
We propose quantum Boolean networks, which can be classified as deterministic reversible asynchronous Boolean networks. This model is based on the previously developed concept of quantum Boolean functions.
Mario Franco   +3 more
doaj   +1 more source

Synchronization of Boolean networks with chaos‐driving and its application in image cryptosystem

open access: yesIET Image Processing, 2023
This paper proposes a Boolean network model with high dimensional chaos driving and investigates the synchronization of the chaos‐driven Boolean network with a semi‐tensor product.
Peng‐Fei Yan   +4 more
doaj   +1 more source

Interpolative Boolean Networks [PDF]

open access: yesComplexity, 2017
Boolean networks are used for modeling and analysis of complex systems of interacting entities. Classical Boolean networks are binary and they are relevant for modeling systems with complex switch-like causal interactions. More descriptive power can be provided by the introduction of gradation in this model.
Vladimir Dobric   +4 more
openaire   +3 more sources

Symmetrizable Boolean networks

open access: yesInformation Sciences, 2023
In this work, we provide a procedure that allows us to transform certain kinds of deterministic Boolean networks on minterm or maxterm functions into symmetric ones, so inferring that such symmetrizable networks can present only periodic points of periods 1 or 2. In particular, we deal with generalized parallel (or synchronous) dynamical systems (GPDS)
Juan A. Aledo   +4 more
openaire   +2 more sources

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