Results 51 to 60 of about 1,008,592 (310)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

SIMULATION AND PERFORMANCE ANALYSIS OF HIGH-EFFICIENCY MULTILEVEL BOOST CONVERTER

open access: yesEdusaintek
This research aims to optimize the efficiency of the boost converter with a cascaded technique to increase efficiency with a more complex circuit, using two Boost Converters assembled in series and two PWM signals so that the circuit performance is more
Zahratul Laily   +2 more
doaj   +1 more source

Composite model predictive control for the boost converter and two-phase interleaved boost converter

open access: yesFrontiers in Energy Research, 2023
This article compares the conventional model predictive control (MPC) and active disturbance rejection control (ADRC) with a novel MPADRC technique for controlling a non-minimum phase behavior in the DC–DC boost converter.
Muhammad Adnan Samad   +6 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Analysis and Implementation of High-Performance DC-DC Step-Up Converter for Multilevel Boost Structure

open access: yesFrontiers in Energy Research, 2019
The conventional DC-DC converters such as SEPIC, boost converter, etc. produces large voltage ripples in multilevel converter systems. For that reason, in this paper, a new DC-DC converter topology is proposed, and the performance is analyzed.
M. Premkumar, C. Kumar, R. Sowmya
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Novel immense configurations of boost converter for renewable energy application

open access: yesThe Journal of Engineering, 2019
A three-immense configurations of boost converter for renewable energy application is presented here. The voltage lift switched inductor (VLSI) structure is pledged to extra high-voltage conversion.
Pandav Kiran Maroti   +4 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Design and implementation of a high step-up boost-fly back converter with soft switching [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2017
In this paper a new soft switching boost-flyback converter is introduced to eliminate conventional boost-flyback converter problems in the high voltage applications. The main application of this converter is conction of PV system to the power system.
Ghasem Haghshenas   +1 more
doaj  

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