Results 101 to 110 of about 370,101 (314)

Ensemble Machine Learning on the Fusion of Sentinel Time Series Imagery with High-Resolution Orthoimagery for Improved Land Use/Land Cover Mapping

open access: yesRemote Sensing
In the United States, several land use and land cover (LULC) data sets are available based on satellite data, but these data sets often fail to accurately represent features on the ground.
Mukti Ram Subedi   +6 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Flexible semiparametric mixed models [PDF]

open access: yes, 2005
In linear mixed models the influence of covariates is restricted to a strictly parametric form. With the rise of semi- and nonparametric regression also the mixed model has been expanded to allow for additive predictors.
Reithinger, Florian, Tutz, Gerhard
core   +1 more source

New Software for the Fast Estimation of Population Recombination Rates (FastEPRR) in the Genomic Era

open access: yesG3: Genes, Genomes, Genetics, 2016
Genetic recombination is a very important evolutionary mechanism that mixes parental haplotypes and produces new raw material for organismal evolution. As a result, information on recombination rates is critical for biological research. In this paper, we
Feng Gao   +3 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Multinomial Logit Models with Implicit Variable Selection [PDF]

open access: yes, 2010
Multinomial logit models which are most commonly used for the modeling of unordered multi-category responses are typically restricted to the use of few predictors. In the high-dimensional case maximum likelihood estimates frequently do not exist. In this
Tutz, Gerhard, Zahid, Faisal Maqbool
core   +1 more source

Application of bagging, boosting and stacking to intrusion detection

open access: yes, 2012
This paper investigates the possibility of using ensemble algorithms to improve the performance of network intrusion detection systems. We use an ensemble of three different methods, bagging, boosting and stacking, in order to improve the accuracy and ...
Syarif, Iwan   +3 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Boosting Correlation Based Penalization in Generalized Linear Models [PDF]

open access: yes, 2007
In high dimensional regression problems penalization techniques are a useful tool for estimation and variable selection. We propose a novel penalization technique that aims at the grouping effect which encourages strongly correlated predictors to be in ...
Tutz, Gerhard, Ulbricht, Jan
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong   +10 more
wiley   +1 more source

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