Results 41 to 50 of about 224,408 (267)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Hedging and Boosting Criticism in Dissertation Thesis Reviews

ELOPE
Dissertation thesis reviews within the Czech academic context are, unlike journal article peer reviews, non-blind, non-anonymous, publicly available texts. The key feature of these reviews is evaluation, and they require a substantial amount of facework
Magda Sučková, Petra Zmrzlá
doaj   +1 more source

Performance Analysis of Classification Algorithms on Birth Dataset

IEEE Access, 2020
Generating intuitions from data using data mining and machine learning algorithms to predict outcomes is useful area of computing. The application area of data mining techniques and machine learning is wide ranging including industries, healthcare ...
Syed Ali Abbas, Aqeel Ur Rehman, Fiaz Majeed, Abdul Majid, M. Sheraz Arshed Malik, Zaki Hassan Kazmi, Seemab Zafar   +6 more
doaj   +1 more source

Topic Models Ensembles for AD-HOC Information Retrieval

Information, 2021
Ad hoc information retrieval (ad hoc IR) is a challenging task consisting of ranking text documents for bag-of-words (BOW) queries. Classic approaches based on query and document text vectors use term-weighting functions to rank the documents.
Pablo Ormeño, Marcelo Mendoza, Carlos Valle   +2 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Diverse Models, United Goal: A Comprehensive Survey of Ensemble Learning

CAAI Transactions on Intelligence Technology
Ensemble learning, a pivotal branch of machine learning, amalgamates multiple base models to enhance the overarching performance of predictive models, capitalising on the diversity and collective wisdom of the ensemble to surpass individual models and ...
Ziwei Fan, Zhiwen Yu, Kaixiang Yang, Wuxing Chen, Xiaoqing Liu, Guojie Li, Xianling Yang, C. L. Philip Chen   +7 more
doaj   +1 more source

Exploiting the Regularized Greedy Forest Algorithm Through Active Learning for Predicting Student Grades: A Case Study

Knowledge
Student performance prediction is a critical research challenge in the field of educational data mining. To address this issue, various machine learning methods have been employed with significant success, including instance-based algorithms, decision ...
Maria Tsiakmaki, Georgios Kostopoulos, Sotiris Kotsiantis   +2 more
doaj   +1 more source

RolexBoost: A Rotation-Based Boosting Algorithm With Adaptive Loss Functions

IEEE Access, 2020
We propose a new ensemble algorithm, called RolexBoost (Rotation-Flexible AdaBoost) that can not only secure diversity within an ensemble by rotating the feature axes in conjunction with performing the random subspace method for each bootstrap sample ...
Dong-Hyuk Yang, Hyeong-Jun Lee, Dong-Joon Lim   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source