Results 61 to 70 of about 107,685 (262)

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Bootstrap Tests: How Many Bootstraps? [PDF]

In practice, bootstrap tests must use a finite number of bootstrap samples. This means that the outcome of the test will depend on the sequence of random numbers used to generate the bootstrap samples, and it necessarily results in some loss of power. We
Russell Davidson, James G. MacKinnon
core   +2 more sources

Improving the Reliability of Bootstrap Tests with the Fast Double Bootstrap [PDF]

We first propose two procedures for estimating the rejection probabilities of bootstrap tests in Monte Carlo experiments without actually computing a bootstrap test for each replication. These procedures are only about twice as expensive (per replication)
Russell Davidson, James G. MacKinnon
core   +2 more sources

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Causal bootstrapping

CoRR, 2019
To draw scientifically meaningful conclusions and build reliable models of quantitative phenomena, cause and effect must be taken into consideration (either implicitly or explicitly). This is particularly challenging when the measurements are not from controlled experimental (interventional) settings, since cause and effect can be obscured by spurious,
Max A. Little, Reham Badawy
openaire   +3 more sources

An Advanced Hybrid Boot-LSTM-ICSO-PP Approach for Day-Ahead Probabilistic PV Power Yield Forecasting and Intra-Hour Power Fluctuation Estimation

IEEE Access
Probabilistic forecasting models have been developed over the past years in order to aid in the estimation of the uncertainty of the predictive results. A hybrid, bootstrapping long-short term memory (Boot-LSTM)-based model is proposed in this paper, in ...
Ioannis K. Bazionis, Markos A. Kousounadis-Knousen, Vasileios E. Katsigiannis, Francky Catthoor, Pavlos S. Georgilakis   +4 more
doaj   +1 more source

Implementing the Rearrangement Algorithm: An Example from Computational Risk Management

Risks, 2020
After a brief overview of aspects of computational risk management, the implementation of the rearrangement algorithm in R is considered as an example from computational risk management practice.
Marius Hofert
doaj   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

Interval estimation for minimal clinically important difference and its classification error via a bootstrap scheme

Statistical Theory and Related Fields, 2020
With the improved knowledge on clinical relevance and more convenient access to the patient-reported outcome data, clinical researchers prefer to adopt minimal clinically important difference (MCID) rather than statistical significance as a testing ...
Zehua Zhou, Jiwei Zhao, Melissa Kluczynski   +2 more
doaj   +1 more source