Results 41 to 50 of about 304,135 (266)
The understanding of tinnitus has always been elusive and is largely prevented by its intrinsic heterogeneity. To address this issue, scientific research has aimed at defining stable and easily identifiable subphenotypes of tinnitus.
Robin Guillard +5 more
doaj +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Testing Goodness-of-Fit of Parametric Spatial Trends
The aim of this work is to propose and analyze the behavior of a test statistic to assess a parametric trend surface, that is, a regression model with spatially correlated errors.
Andrea Meilán-Vila +3 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
En este trabajo se comparan métodos para encontrar intervalos de confianza para la función de supervivencia, como los métodos de remuestreo Bootstrap aplicado a los estimadores de Kaplan-Meier y Nelson-Aalen.
JAVIER RAMÍREZ
doaj
Sarah Webb explores how DIYbio strategies are helping biologists in traditional labs do better science.
openaire +2 more sources
Probabilistic models of data sets often exhibit salient geometric structure. Such a phenomenon is summed up in the manifold distribution hypothesis, and can be exploited in probabilistic learning. Here we present normal-bundle bootstrap (NBB), a method that generates new data which preserve the geometric structure of a given data set.
Ruda Zhang, Roger G. Ghanem
openaire +2 more sources
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Este trabajo estudia las ventajas y limitaciones de un test para contrastar la igualdad de las distribuciones de origen de k-muestras independientes. El estadístico propuesto, denominado LGk, está basado en una medida que generaliza la norma L1 entre ...
PABLO MARTÍNEZ-CAMBLOR
doaj
30 pages, 15 figures, 3 tables; v2: minor ...
Echeverri, Alejandro Castedo +2 more
openaire +4 more sources

