Omnichannel integration strategy based on BOPS. [PDF]
Technological innovation and the upgrading of consumer preferences have greatly accelerated the rapid development of the "new retail" omnichannel model.
Meirong Tan +3 more
doaj +2 more sources
Small protein complex prediction algorithm based on protein–protein interaction network segmentation [PDF]
Background Identifying protein complexes from protein-protein interaction network is one of significant tasks in the postgenome era. Protein complexes, none of which exceeds 10 in size play an irreplaceable role in life activities and are also a hotspot ...
Jiaqing Lyu +4 more
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A biomechanical-based approach to scale blast-induced molecular changes in the brain [PDF]
Animal studies provide valuable insights on how the interaction of blast waves with the head may injure the brain. However, there is no acceptable methodology to scale the findings from animals to humans.
Jose E. Rubio +10 more
doaj +2 more sources
A BLADE-ON-PETIOLE orthologue regulates corolla differentiation in the proximal region in Torenia fournieri [PDF]
The three-dimensional shape of a flower is integrated by morphogenesis along different axes. Differentiation along the petal proximodistal axis is tightly linked to the specification of pollinators; however, it is still unclear how a petal patterns this ...
Shihao Su +5 more
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Branched oncolytic peptides target HSPGs, inhibit metastasis, and trigger the release of molecular determinants of immunogenic cell death in pancreatic cancer [PDF]
Immunogenic cell death (ICD) can be exploited to treat non-immunoreactive tumors that do not respond to current standard and innovative therapies. Not all chemotherapeutics trigger ICD, among those that do exert this effect, there are anthracyclines ...
Alessandro Rencinai +7 more
doaj +2 more sources
An Intelligent Logic-Based Mold Breakout Prediction System Algorithm for the Continuous Casting Process of Steel: A Novel Study [PDF]
Mold breakout is one of the significant problems in a continuous casting machine (caster). It represents one of the key areas within the steel production facilities of a steel plant.
Md Obaidullah Ansari +9 more
doaj +2 more sources
Poly ADP-Ribose Polymerase-1 inhibition by 3-aminobenzamide recuperates HEI-OC1 auditory hair cells from blast overpressure-induced cell death [PDF]
Introduction: Poly ADP-Ribose Polymerase-1 (PARP1), a DNA repair enzyme is implicated as a key molecule in the pathogenesis of several neurodegenerative disorders.
Vijaya Prakash Krishnan Muthaiah +2 more
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Cerebral Vasculature Influences Blast-Induced Biomechanical Responses of Human Brain Tissue [PDF]
Multiple finite-element (FE) models to predict the biomechanical responses in the human brain resulting from the interaction with blast waves have established the importance of including the brain-surface convolutions, the major cerebral veins, and using
Dhananjay Radhakrishnan Subramaniam +10 more
doaj +2 more sources
Beneficial Outcome Pathways: A New Mechanistic Framework to Map the Health Effects of Fasting in Metabolic Dysfunction-Associated Steatotic Liver Disease [PDF]
Lifestyle interventions such as fasting are difficult to evaluate using placebo-controlled randomized trials, resulting in fragmented and heterogeneous evidence.
Robin Mesnage, Verena Buchinger
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Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4H)-yl)methyl) pyridin-1-ium derivatives (BOPs) as potential dual inhibitors of acetylcholinesterase and butyrylcholinesterase [PDF]
Alzheimer's disease (AD), is among the most growing neurodegenerative diseases, which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and cortex. Emerging of the dual Acetylcholinesterase (AChE)/Butyrylcholinesterase (BuChE)
Samaneh Zarei +7 more
doaj +2 more sources

