Results 1 to 10 of about 5,783 (269)

Omnichannel integration strategy based on BOPS. [PDF]

open access: yesPLoS ONE, 2023
Technological innovation and the upgrading of consumer preferences have greatly accelerated the rapid development of the "new retail" omnichannel model.
Meirong Tan   +3 more
doaj   +2 more sources

Small protein complex prediction algorithm based on protein–protein interaction network segmentation [PDF]

open access: yesBMC Bioinformatics, 2022
Background Identifying protein complexes from protein-protein interaction network is one of significant tasks in the postgenome era. Protein complexes, none of which exceeds 10 in size play an irreplaceable role in life activities and are also a hotspot ...
Jiaqing Lyu   +4 more
doaj   +2 more sources

A biomechanical-based approach to scale blast-induced molecular changes in the brain [PDF]

open access: yesScientific Reports, 2022
Animal studies provide valuable insights on how the interaction of blast waves with the head may injure the brain. However, there is no acceptable methodology to scale the findings from animals to humans.
Jose E. Rubio   +10 more
doaj   +2 more sources

A BLADE-ON-PETIOLE orthologue regulates corolla differentiation in the proximal region in Torenia fournieri [PDF]

open access: yesNature Communications, 2023
The three-dimensional shape of a flower is integrated by morphogenesis along different axes. Differentiation along the petal proximodistal axis is tightly linked to the specification of pollinators; however, it is still unclear how a petal patterns this ...
Shihao Su   +5 more
doaj   +2 more sources

Branched oncolytic peptides target HSPGs, inhibit metastasis, and trigger the release of molecular determinants of immunogenic cell death in pancreatic cancer [PDF]

open access: yesFrontiers in Molecular Biosciences
Immunogenic cell death (ICD) can be exploited to treat non-immunoreactive tumors that do not respond to current standard and innovative therapies. Not all chemotherapeutics trigger ICD, among those that do exert this effect, there are anthracyclines ...
Alessandro Rencinai   +7 more
doaj   +2 more sources

An Intelligent Logic-Based Mold Breakout Prediction System Algorithm for the Continuous Casting Process of Steel: A Novel Study [PDF]

open access: yesMicromachines, 2022
Mold breakout is one of the significant problems in a continuous casting machine (caster). It represents one of the key areas within the steel production facilities of a steel plant.
Md Obaidullah Ansari   +9 more
doaj   +2 more sources

Poly ADP-Ribose Polymerase-1 inhibition by 3-aminobenzamide recuperates HEI-OC1 auditory hair cells from blast overpressure-induced cell death [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Poly ADP-Ribose Polymerase-1 (PARP1), a DNA repair enzyme is implicated as a key molecule in the pathogenesis of several neurodegenerative disorders.
Vijaya Prakash Krishnan Muthaiah   +2 more
doaj   +2 more sources

Cerebral Vasculature Influences Blast-Induced Biomechanical Responses of Human Brain Tissue [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Multiple finite-element (FE) models to predict the biomechanical responses in the human brain resulting from the interaction with blast waves have established the importance of including the brain-surface convolutions, the major cerebral veins, and using
Dhananjay Radhakrishnan Subramaniam   +10 more
doaj   +2 more sources

Beneficial Outcome Pathways: A New Mechanistic Framework to Map the Health Effects of Fasting in Metabolic Dysfunction-Associated Steatotic Liver Disease [PDF]

open access: yesJournal of Nutrition and Metabolism
Lifestyle interventions such as fasting are difficult to evaluate using placebo-controlled randomized trials, resulting in fragmented and heterogeneous evidence.
Robin Mesnage, Verena Buchinger
doaj   +2 more sources

Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4H)-yl)methyl) pyridin-1-ium derivatives (BOPs) as potential dual inhibitors of acetylcholinesterase and butyrylcholinesterase [PDF]

open access: yesHeliyon, 2021
Alzheimer's disease (AD), is among the most growing neurodegenerative diseases, which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and cortex. Emerging of the dual Acetylcholinesterase (AChE)/Butyrylcholinesterase (BuChE)
Samaneh Zarei   +7 more
doaj   +2 more sources

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