Results 151 to 160 of about 2,308,949 (362)

Beyond the border : Border bottlenecks hamper trade [PDF]

open access: yes
Mexico ; North American Free Trade Agreement ; Texas ...
Jay Campbell, Keith Phillips
core  

Cross-Border interoperability for Cooperative, Connected and Autonomous Driving

open access: green, 2021
José Eugenio Naranjo   +8 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Bordering Capabilities versus Borders: Implications for National Borders

open access: yes, 2015
State sovereignty is usually understood as the State’s monopoly of authority over a particular territory, demarcated by reasonably established geographic borders. Today, it is becoming evident that even as national territories remain bounded by traditional geographic borderlines, globalization is causing novel types of ‘borderings’ to multiply; these ...
openaire   +2 more sources

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