Results 131 to 140 of about 2,308,949 (362)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

No. 21: Cross-Border Raiding and Community Conflict in the Lesotho-South African Border Zone [PDF]

, 2001
Movement backwards and forwards across borders for work is often considered to be the primary form of unauthorized movement in Southern Africa. In southern Lesotho, a new and particularly dangerous form of two-way cross-border movement has become ...
Cekwane, Tsepang, Kynoch, Gary, Mohapi, Booi, Mohapi, Mampolokeng, Phakisi, Ntsoaki, Seithleko, Palesa, Ulicki, Theresa   +6 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The impact of after-hours messaging on job stress and burnout among Taiwan’s border police: the roles of social support and coping strategies

Humanities & Social Sciences Communications
With the advancement of technology, communication software is increasingly facilitating interaction between organizations and employees. However, its unrestricted accessibility often blurs the line between work and personal life.
Nein-Tsu Chiang, Rui-Hsin Kao, Hsiang-Yu Ma, Cheng-Chung Cho   +3 more
doaj   +1 more source

Borders Manifest: Racializing the Nicaraguan Refugee in Costa Rica [PDF]

, 2019
I look to border responses of North American countries as refugees and migrants move across them to argue that border responses racialize the foreign other in receiving countries.
Twidwell, Theodore B.
core   +1 more source

Interest Convergence and Higher Education Funding: The South Texas/Border Initiative [PDF]

, 2019
Erin Doran
openalex   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Analytical Solutions for the Nonlinear Stochastic Fractional KdV Equation: An application of the Generalized Riccati Equation Mapping Method

Journal of Applied Science and Engineering
The article examines the fractional stochastic Korteweg-de Vries (FSKdV) equation, with a focus on space-time white noise and conformable fractional derivatives (CFD).
Abaker A. Hassaballa, Ali Satty, Mohyaldein Salih, Ahmed M. A. Adam, Omer M. A. Hamed, Zakariya M. S. Mohammed, Ashraf F. A. Mahmoud, Elzain A. E. Gumma   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Incidence of Gallstones in Patients with Obesity After Bariatric Surgery in Northern Saudi Arabia: A Cross-Sectional Study

Clinics and Practice
Background/Objectives: Gallstone formation (cholelithiasis) is a common and important consequence following bariatric surgery, though regional data from the Northern Border Region are limited.
Abdulrahman Omar A. Alali, Abdualaziz Fayez Alhumidi Alanazi, Mohammed Abdulaziz M. Albarghash, Rakan Nasser Abdullah Alruweli, Mohammed Bader H. Alanazi, Ibrahim Farhan B. Alanazi, Turkey Saleh H. Alrowaily, Rakan Khalid Marzouq Alanazi, Baraah AbuAlsel, Fadih Nada M. Alenezi, Rashad Qasem Ali Othman, Manal S. Fawzy   +11 more
doaj   +1 more source