Results 121 to 130 of about 2,308,949 (362)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Regulation of the rabbit ileal brush-border Na+/H+ exchanger by an ATP-requiring Ca++/calmodulin-mediated process. [PDF]
Richard P. Rood +9 more
openalex +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Coming NAFTA Crash: The Deadly Impact of a Secret NAFTA Tribunal's Decision to Open U.S. Highways to Unsafe Mexican Trucks [PDF]
Report documents that Mexico's truck safety regulations are virtually non-existent, that Mexican trucks have far more safety deficiencies than U.S.
Darshana Patel +3 more
core
Zaire (Congo): resurgence of trypanosomiasis (“patients within borders”) [PDF]
Jacques Pépin
openalex +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
POST study on Pharmacogenetics
D. Cope, P. Border
doaj +1 more source
The sun out-stretched its bright arms in an embrace with the mesquite trees that beckoned upwards. The wind greeted the clothes drying upon delicate wire while my mother meticulously placed white towels in the light and the jeans under the shade of the ...
Castro, Alicia A.
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