Results 61 to 70 of about 2,284,562 (345)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Awareness About Epilepsy Among Schoolteachers in the Northern Border Region, Saudi Arabia
Dubai Medical JournalIntroduction: Epilepsy is a worldwide neurological problem. First aid management is essential to control the fits and minimize the complications. This study aims to evaluate the awareness of epilepsy among schoolteachers in the Northern Border Region ...
Shehab Ahmed Alenazi +6 more
doaj +1 more source
Rhinology journal, 2015 The last 20 years of the last century, that sounds long ago but was actually the time that many of us already practiced in Rhinology or received their training, was I think the time of endoscopic sinus surgery. We learned all the possibilities of the endoscope, first mainly in limited inflammatory disease but later also because of the development of ...
openaire +4 more sources
Transgressive urbanism : borderlands and urban informality of american cities along the panamerican highway [PDF]
, 2013 This study explores the ways in which political boundaries can be trespassed in order to develop subaltern forms of urbanism and edge conditions, mainly to the comparative study of border cities in the Americas, predominantly ruled by informal economies,
Suau, Cristian
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Current Utilisation and Challenges of Point-of-Care Ultrasound in Emergency Department Settings of Saudi Arabia: A Mixed Method Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Point-of-care Ultrasound (POCUS) has transformed emergency medicine by providing immediate, non invasive diagnostic imaging directly at the patient’s bedside.
Muhammad Omer Afzal Bhatti +3 more
doaj +1 more source
THE CRISIS PLATFORM: A CROSS-BORDER PLATFORM FOR RISK ASSESSMENT AND MANAGEMENT [PDF]
, 2023 Antonella Meo +17 more
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
, 2019 Work on this chapter received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 842176.
openaire +2 more sources
The Texas border community has historically been the state's most disadvantaged area. However, the last decade has seen dramatic improvements in unemployment and other economic factors. This series of nine articles explores issues important to the region'
anonymous
core +1 more source