Results 71 to 80 of about 461,725 (268)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Developing a quality assessment model (QAM) using logical prediction: Binary validation

International Journal of Assessment Tools in Education
This study focuses on evaluating the quality of competency transfer through various assessment methods and results, considering diverse stakeholder perspectives.
Sameer Mohammed Majed Dandan, Odai Falah Mohammad Al-ghaswyneh   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Numerical analysis of rainfall-induced slope instability using a reduced-scale model

Magazine of Civil Engineering
The climatic changes induce now more and more serious environmental problems such as landslides, especially in arid and semi-arid countries where rainfalls happen with high and short duration intensity.
Jamei Mehrez, Alassaf Yahya
doaj   +1 more source

Borders:

, 2022
Like the Berlin Wall, borders have been known to inculcate pain and sufffering, potentially trickling down across generations. Some borders are less salient, and their efffects less obvious, but they are notable catalysts of change nonetheless. This fijinal chapter summarizes how religion, education, names, and literacy have featured
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Toxicological studies on commercial hair dye brand commonly used in Saudi Arabia: histological study of the liver, kidney, heart, and testis

Journal of Basic and Applied Zoology, 2018
Background Hair dye is commonly used in the Kingdom of Saudi Arabia (KSA). Poisoning occurs when someone swallows dye or tint used to color hair and is considered one of the most significant causes of intentional self-harm.
Turki M. Al-Shaikh, Khaznah S. Alkaseb, Mahmoud M. E. Mudawi, Abdelhadi Y. A. Yassin, Rami S. Habeballa, Shiemaa D. Alzain   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Assessment of Students’ Perception Regarding the Learning Experience in the Virtual Pharmacology Laboratory

Dubai Medical Journal
Objective: The current study was conducted to evaluate students’ feedback on the virtual pharmacology classes among the second-year students in Faculty of Medicine, Northern Border University, Saudi Arabia.
Bandar T. Alenezi, Elhassan Hussein Eltom, Muhammad Jan, Samah Gaafar Alshygi, Rahma Hamayun, Syed Sajid Shah, Ekramy Elmorsy   +6 more
doaj   +1 more source