Results 81 to 90 of about 6,609,888 (231)

Cross-Border Work in Europe. Realities and Challenges

Living in one country and working in another is a daily reality for thousands of people in Europe. The contributions in this book analyze the many facets of cross-border worker flows, identifying similarities and differences from one area to another. The
Belkacem, Rachid, WILLE, Christian, PIGERON-PIROTH, Isabelle   +2 more
core   +1 more source

The Communal Roots of Mexico’s Maquila Industry: Urbanization, Land, and Inequality in Ciudad Juárez, 1960–2000

Latin American Research Review
This article analyzes the urbanization and privatization of communal lands (ejidos) in Ciudad Juárez, Mexico, via a computer vision model that utilizes Google Street View (GSV) and Geographic Information System (GIS) imagery.
Mateo J. Carrillo, Jonatan Pérez
doaj   +1 more source

Spatial distribution and environmental factors associated to phlebotomine fauna in a border area of transmission of visceral leishmaniasis in Mato Grosso do Sul, Brazil

Parasites & Vectors, 2014
Background Mato Grosso do Sul has been undergoing a process of urbanization which results in loss of native vegetation. This withdrawal makes vectors of man and domestic animals closer, causing changes in the epidemiology of diseases such as American ...
Ana Rachel Oliveira de Andrade, Baldomero Antonio Kato da Silva, Geucira Cristaldo, Sonia Maria Oliveira de Andrade, Antonio Conceição Paranhos Filho, Alisson Ribeiro, Mirella Ferreira da Cunha Santos, Renato Andreotti   +7 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Spatio-Temporal Database of Places Located in the Border Area

ISPRS International Journal of Geo-Information, 2018
As a result of changes in boundaries, the political affiliation of locations also changes. Data on such locations are now collected in datasets with reference to the present or to the past space.
Albina Mościcka, Marta Kuźma
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Impact of Trade with Border Effect on GDP per Capita: Global Evidence

Economies
Many countries worldwide share borders that offer several benefits, such as easier access, faster knowledge transfer, and more efficient trade diplomacy.
Hansen Tandra, I Gusti Ayu Putu Mahendri, Sujianto Sujianto, Bahtiar Rifai, Zamroni Salim, Helena da Silva, Yulia Pujiharti   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

DEVELOPMENT STRATEGY OF AGRICULTURAL SECTOR FOR SUPPORT THE ECONOMY ACTIVITIES IN BORDER AREAS OF WEST KALIMANTAN

Jurnal Aplikasi Manajemen, 2018
The purpose of this study is to identify development strategy of the agricultural sector for supportthe economic activities in border areas of West Kalimantan.
Imelda Imelda
doaj   +1 more source