Results 61 to 70 of about 275,260 (263)
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
THE PROTECTION OF NORTH EAST BORDER AREAS AND CROSS BORDER INSURGENCY
SCHOLARLY RESEARCH JOURNAL FOR HUMANITY SCIENCE AND ENGLISH LANGUAGE, 2021 The armed insurrections in north-east India have tested the Indian military might for over four decades. The region is characterised by widespread conflicts which are related to the geography of the region, the multi ethnicity of its population and the political and economic feeding grounds of discontent. The conflict dynamics range from insurgency for
openaire +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The influence of the border factor on the partisan movement of Eastern Trans-Baikal region
Известия высших учебных заведений. Поволжский регион: Гуманитарные наукиBackground. The article examines the poorly studied issue of the relationship be-tween the partisans of the Eastern Trans-Baikal during the Civil War with the authorities of the border regions of China and Mongolia.
D.A. Taskin
doaj +1 more source
Shuitu baochi yanjiu, 2021 After entering the 21st century, the development of Yanbian Korean Autonomous Prefecture in all aspects has been further improved, and human activities have seriously affected changes in landscape patterns and ecological service functions.
YU Yuan, LI Mingyu, HAN Xulong, LIU Hui
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Zhongguo gonggong weishengObjectiveTo understand the prevalence and influencing factors of comorbid chronic diseases among adult rural residents in the border areas of Jilin province, and to provide a reference for the prevention and control of chronic diseases among local ...
Wangen SHEN +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source