Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
La fallida política común de inmigración en la Unión Europea
Vergentis. Revista de Investigación de la Cátedra Internacional Conjunta Inocencio III, 2019 Despite the fact that the EU intends to be a common space, in which the different policies are adopted among all member states, the search for a “common policy on migration”, which is framed in the purpose of making Europe a Common space of freedom ...
Juan Manuel Goig Martínez
doaj
Border Control for Infectious Respiratory Disease Pandemics: A Modelling Study for H1N1 and Four Strains of SARS-CoV-2. [PDF]
Viruses, 2023 Lim NW, Lim JT, Dickens BL.
europepmc +1 more source
On the institutional design of burden sharing when financing external border enforcement in the EU [PDF]
Illegal immigration affects not only EU member states at the Mediterranean Sea but also more Northern states due to open internal borders and onward migration.
Claus-Jochen Haake +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Perspectives of public health professionals on border control practices for COVID-19 management in Europe. [PDF]
Public Health, 2022 Dieminger L +3 more
europepmc +1 more source
Enhancing the Benefits for India and Other Developing Countries in the Doha Development Agenda Negotiations [PDF]
When firms from developed markets acquire firms in emerging markets, marketcapitalization-weighted monthly joint returns show a statistically significant increase of 1.8%.
Anusha Chari +2 more
core
Processes underlying rabies virus incursions across US–Canada Border as revealed by whole-genome phylogeography [PDF]
Disease control programs aim to constrain and reduce the spread of infection. Human disease interventions such as wildlife vaccination play a major role in determining the limits of a pathogen’s spatial distribution.
Biek, Roman +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
An Optimal Surveillance Measure Against Foot-and-Mouth Disease in the United States [PDF]
Surveillance programs on farms and in the local environment provide an essential protection against the importation and spread of exotic diseases. Combined with border quarantine measures, these programs protect both consumers and producers from major ...
Che, Tuong Nhu +2 more
core +1 more source