Results 71 to 80 of about 1,273,770 (305)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On 4 May 2015, the Australian national broadcaster’s current affairs programme Four Corners aired an episode titled ‘Slaving Away: The dirty secrets behind Australia’s fresh food’, that provided revelations of labour exploitation of migrant workers on ...
Anna Szörényi
doaj +1 more source
Pollution Control, Competitiveness, and Border Tax Adjustment [PDF]
This paper explores in a general equilibrium framework the welfare and sectoral implications of an optimally designed system of border tax adjustments (BTA) on the imports of energy-intensive industries.
Yazid Dissou
core
Control and Responsibility in European Union Migration Law and Policy – A study of Externalisation and Privatisation [PDF]
Introduction: Member States of the European Union (“Member State(s)” or “the State(s)”), are long associated with seeking to preserve their authority over migration control and border management.
McNamara, Frank
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Controlling the Mediterranean space through surveillance
The efforts to strengthen the control over the European Union’s (EU) external borders currently revolve around the reinforcement of the surveillance capabilities of the Member States.
Maria Gabrielsen Jumbert
doaj +1 more source
In the town of Briançon (Hautes-Alpes), on the French side of the French-Italian border, the border police (PAF) controls for those who have crossed the border illegally by operating on a discretionary basis. Mobile police practices include tracking down
Sarah Bachellerie
doaj +1 more source
International Meeting on the Enabling Environment for Philanthropy [PDF]
Worldwide, philanthropy is facing a concerning trend as civil society organizations deal with heightened control and excessive, unwarranted restrictions on funding, both locally and internationally. In March 2016, WINGS hosted a workshop to discuss these
core
The Politics of Exhaustion: Immigration Control in the British-French Border Zone [PDF]
Within a climate of growing anti-immigration and populist forces gaining traction across Europe, and in response to the increased number of prospective asylum seekers arriving in Europe, recent years have seen the continued hardening of borders and a ...
Welander, M., Welander, M.
core

