Results 71 to 80 of about 296,467 (311)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Contemporary Migratory Movements: Between Border Control and the Production of Its Illegality. A Dialogue with Nicholas De Genova.
Soledad Álvarez
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Transit Migration in Armed Conflicts: New Trends and Challenges for International Policy
This study analyzes the transformation of migration routes and volumes through transit states and the resulting challenges for international policy amid armed conflicts.
Lyudmila Korigova +2 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Border management and post - 9/11 state security concerns: implications for the Bangladesh-India border [PDF]
The history of Bangladesh-India border started with the partition in 1947. Bangladesh has inherited the whole India-East Pakistan border as well as the disputes and unresolved issues following her independence on 16 December, 1971. In the pre-9/11 period,
Shewly, Hosna Jahan
core
This study employs a single case study to build an initial understanding of a case or an evaluation of a fatal attack by Uzbekistan detainees affiliated with a terrorist group to the immigration office at the North Jakarta Immigration Office.
Yanos Okterano, Heru Susetyo
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Externally Driven Border Control in West Africa: Local Impact and Broader Ramifications
Over the last two decades and with notable increase since 2015, millions of euros have been invested in territorial border governance in West Africa.
Talleraas, Cathrine
core +1 more source

