Results 21 to 30 of about 249,333 (164)

CHIKV mRNA vaccines encoding conserved structural/envelope proteins confer broad cross-lineage protection against infection

Signal Transduction and Targeted Therapy
With the broad spread of the chikungunya virus (CHIKV), there is an increasing demand for more effective and broadly protective vaccines. Here, we designed CHIKV mRNA vaccines containing full-length structural proteins or part of structural proteins ...
Xiaoming Liang, Yanan Zhou, Yun Yang, Qianqian Li, Junbin Wang, Bai Li, Hao Yang, Cong Tang, Wenhai Yu, Haixuan Wang, Qing Huang, Hongyu Chen, Yuhuan Yan, Ran An, Dongdong Lin, Wenqi Quan, Yong Zhang, Yanwen Li, Xuena Du, Yuxia Yuan, Longhai Yuan, Jian Zhou, Qiangming Sun, Youchun Wang, Shuaiyao Lu   +24 more
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Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus

MedComm
Chikungunya virus (CHIKV) is a mosquito‐borne alphavirus that is primarily known for causing severe joint and muscle symptoms, but its pathological effects have extended beyond these tissues. In this study, we conducted a comprehensive proteomic analysis
Dongdong Lin, Cong Tang, Junbin Wang, Yun Yang, Hao Yang, Yanan Zhou, Wenhai Yu, Bai Li, Qing Huang, Haixuan Wang, Ran An, Xiaoming Liang, Yuhuan Yan, Longhai Yuan, Xuena Du, Yuxia Yuan, Yanwen Li, Shuaiyao Lu   +17 more
doaj   +1 more source

Review on mechanisms and therapeutic advances in inorganic arsenic-induced reproductive system disorders

All Life
Inorganic arsenic (iAs), a toxic metalloid and recognized carcinogen, is widely distributed in the natural environment. Human exposure to iAs occurs via multiple pathways, leading to its accumulation and adverse effects on the human body.
Chengke Lu, Xinyu Li, Xin Zhao, Zhiyuan Zou, JiaXin Zhao, Jia Liu, Ying Zhao, Wei Zou   +7 more
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Prophylactic Protection Against Salmonella typhimurium Infection by Single-Atom Zinc Catalysts

Nanomaterials
Zinc oxide promotes poultry growth, but it tends to agglomerate. This necessitates high doses and leads to environmental contamination from unabsorbed, excreted zinc. Undigested zinc is excreted and can enter the food chain, increasing the probability of
Ling Teng, Hesheng Pan, Zhongwei Chen, Junfeng Sun, Yanwen Zhang, Changting Li, Zhe Pei, Chunxia Ma, Yu Gong, Huili Bai, Leping Wang, Yan Huang, Jing Wang, Chao Zhao, Xian Li, Yangyan Yin, Yingyi Wei, Hao Peng   +17 more
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Development of a Double-Antibody Sandwich ELISA Based on a Monoclonal Antibody against the Viral NS1 Protein for the Detection of Chicken Parvovirus

Pathogens
Chicken parvovirus (ChPV) infection can cause runting-stunting syndrome (RSS) in chickens. There is currently no commercially available vaccine for controlling ChPV, and ChPV infection in chickens is widespread globally.
Minxiu Zhang, Jianqi Liao, Zhixun Xie, Yanfang Zhang, Sisi Luo, Meng Li, Liji Xie, Qing Fan, Tingting Zeng, Jiaoling Huang, Sheng Wang   +10 more
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Population movements, borders, and Chagas disease

Memórias do Instituto Oswaldo Cruz, 2022
Currently, Chagas disease is a complex global health problem with local and global implications. In the present article, we approach this complexity from the perspective of human mobility and its effects on people's health in places of origin and in transit and destination.
Andrea Avaria, Laia Ventura-Garcia, Mariana Sanmartino, Carlos Van der Laat   +3 more
openaire   +6 more sources

Simultaneous Differential Detection of H5, H7, H9 and Nine NA Subtypes of Avian Influenza Viruses via a GeXP Assay

Microorganisms
H5, H7 and H9 are the most important subtypes of avian influenza viruses (AIVs), and nine neuraminidase (NA) subtypes (N1–N9) of AIVs have been identified in poultry.
Sisi Luo, Zhixun Xie, Meng Li, Dan Li, Minxiu Zhang, Zhihua Ruan, Liji Xie, Sheng Wang, Qing Fan, Yanfang Zhang, Jiaoling Huang, Tingting Zeng   +11 more
doaj   +1 more source

Analysis of Three-Dimensional Scar Architecture and Conducting Channels by High-Resolution Contrast-Enhanced Cardiac Magnetic Resonance Imaging in Chagas Heart Disease

Revista da Sociedade Brasileira de Medicina Tropical, 2022
Background: We aimed to describe the morphology of the border zone of viable myocardium surrounded by scarring in patients with Chagas heart disease and study their association with clinical events.
João Bosco de Figueiredo Santos, Ilan Gottlieb, Eduardo Marinho Tassi, Gabriel Cordeiro Camargo, Jacob Atié, Sérgio Salles Xavier, Roberto Coury Pedrosa, Josep Brugada, Roberto Magalhães Saraiva   +8 more
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A sandwich amperometric immunosensor for the detection of fowl adenovirus group I based on bimetallic Pt/Ag nanoparticle-functionalized multiwalled carbon nanotubes

Scientific Reports
An enzyme-free sandwich amperometric immunosensor based on bimetallic Pt/Ag nanoparticle (Pt/AgNPs)-functionalized chitosan (Chi)-modified multiwalled carbon nanotubes (MWCNTs) as dual signal amplifiers and Chi-modified MWCNTs (MWCNTs-Chi) as substrate ...
Jiaoling Huang, Zhixun Xie, Sisi Luo, Meng Li, Liji Xie, Qing Fan, Tingting Zeng, Yanfang Zhang, Minxiu Zhang, Zhiqin Xie, Sheng Wang, Dan Li, You Wei, Xiaofeng Li, Lijun Wan, Hongyu Ren   +15 more
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The modified mRNA vaccine protects immunocompromised AG129 mice from lethal challenge and multi-tissue infection by Zika virus

Emerging Microbes and Infections
The multiple epidemics of Zika virus (ZIKV) posed a substantial threat to public health. Clinical evidence suggests that ZIKV could break through the blood–brain, blood-placenta, and blood-testis barriers, leading to severe outcomes such as congenital ...
Yuhuan Yan, Junbin Wang, Hao Yang, Yun Yang, Longhai Yuan, Cong Tang, Yanan Zhou, Qing Huang, Wenhai Yu, Xiaoming Liang, Dongdong Lin, Yanwen Li, Xuena Du, Yuxia Yuan, Rui Peng, Jiali Xu, Zhaolan Guo, Wenhao Xie, Wenqi Quan, Hongyu Chen, Jian Zhou, Shuaiyao Lu, Xiaozhong Peng   +22 more
doaj   +1 more source